Frequency and distribution of asymptomatic brain lesions in patients with β-thalassemia intermedia
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Summary
The lack of significant correlation between lesions and regular blood transfusions could be related to the treatment with HU in untransfused patients, which increased fetal hemoglobin levels and improved the morphology and the pathological indices of the red blood cells.
- Type
- article
- Published
- 2012-07-24
- Cited by
- 20
- References
- 32
- OpenAlex
- https://openalex.org/W2119039866
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:1358184
Keywords
Thrombocytosis, Medicine, Splenectomy, Asymptomatic, Gastroenterology
References
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- Thalassemia major - on the verge of bleeding or thrombosis?
- Asymptomatic brain magnetic resonance imaging abnormalities in splenectomized adults with thalassemia intermedia
- Phosphatidylserine in the outer leaflet of red blood cells from β‐thalassemia patients may explain the chronic hypercoagulable state and thrombotic episodes
- Genotype–phenotype relationship of patients with β-thalassemia taking hydroxyurea: a 13-year experience in Iran
- Hematologic and Clinical Responses of Thalassemia Intermedia Patients to Hydroxyurea During 6 Years of Therapy in Iran
- Hydroxyurea downregulates endothelin-1 gene expression and upregulates ICAM-1 gene expression in cultured human endothelial cells
- Protein C and antithrombin III in polytransfused thalassemic patients.
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- Lessons From the Stroke Prevention Trial in Sickle Cell Anemia (STOP) Study
- MR imaging of the brain: findings in asymptomatic patients with thalassemia intermedia and sickle cell-thalassemia disease.
- Hydroxyurea for sickle cell disease in children and for prevention of cerebrovascular events: the Belgian experience.
- Clinical silent cerebral infarct (SCI) in patients with thalassemia diseases assessed by magnetic resonance imaging (MRI).
- Magnetic resonance imaging to determine the incidence of brain ischaemia in patients with β-thalassaemia intermedia
- Hydroxyurea Therapy Mobilises Arachidonic Acid from Inner Cell Membrane Aminophospholipids in Patients with Homozygous Sickle Cell Disease
- Adhesion molecules and hydroxyurea in the pathophysiology of sickle cell disease
Cited by
- Non-transfusion-dependent thalassemia and thalassemia intermedia: epidemiology, complications, and management
- The frequency of silent cerebral ischemia in patients with transfusion-dependent β-thalassemia major
- Neurological complications of beta-thalassemia
- Hydroxyurea Treatment in Transfusion-Dependent β-Thalassemia Patients
- Cerebral infarction in β-thalassemia intermedia: breaking the silence.
- Guidelines for Diagnosis and Management of Beta-Thalassemia Intermedia
- Evaluation of the Relationship Between Hb F Levels and Nucleated Red Blood Cells with Morbidity in Non Transfusion-Dependent Thalassemia Patients
- Frequency of silent cerebral ischemia in patients with transfusion-dependent β-thalassemia major compared to healthy individuals
- Revisiting beta thalassemia intermedia: past, present, and future prospects
- Hypercoagulability and Vascular Disease.
- Neuroimaging Abnormalities in Patients With Nontransfusion-dependent Thalassemia
- No evidence of increased cerebrovascular involvement in adult neurologically‐asymptomatic β‐Thalassaemia. A multicentre multimodal magnetic resonance study
- Attention, response inhibition and brain event‐related potential alterations in adults with beta‐thalassaemia major
- Frequency of silent brain lesions and aspirin protection evaluation over 3 years follow-up in beta thalassemia patients
- Thromboembolic Events in Severe Thalassemia Syndromes
- Cerebrovascular Complications of Anemia
- Vascular Brain Damage in Thalassemia Syndrome: An Emerging Challenge
- Long-term Results of Splenectomy in Transfusion-dependent Thalassemia
- Imaging of Central Nervous System Involvement in Pediatric Hematologic Disorders
- Modified Magnetic Resonance Imaging Burden of Cerebral Small Vessel Disease and Related Risk Factors in Patients With Thalassemia
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