Design of β-amino acid with backbone-side chain interactions: stabilization of 14/15-helix in α/β-peptides.
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Summary
The designed monomer enlarges the opportunities for the synthesis of peptides with novel conformations and expands the repertoire of the foldamers, suggesting that the side chain-backbone interactions are crucial in the stabilization of the desired folding propensity.
- Type
- article
- Published
- 2012-08-08
- Cited by
- 24
- References
- 68
- OpenAlex
- https://openalex.org/W22816665
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:12157214
Keywords
Computer science
References
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- Tetra-n-butylammonium fluoride: an efficient base for aza-Michael addition—synthesis of glycosyl β-amino acid esters
Cited by
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- Stabilisation of a short α‐helical VIP fragment by side chain to side chain cyclisation: a comparison of common cyclisation motifs by circular dichroism
- Synthesis and secondary conformations of homochiral β-oligopeptides containing aryl side chains
- Sugar furanoid trans-vicinal diacid as a γ-turn inducer: synthesis and conformational study.
- Synthesis of new β(2,2)-amino acids with carbohydrate side chains: impact on the synthesis of peptides.
- Three-residue turn in β-peptides nucleated by a 12/10 helix.
- Tetrahydrofuran Amino Acids of the Past Decade
- Synthesis of Building Blocks for Carbopeptoids and Their Triazole Isoster Assembly
- New helical folds in α-peptides with alternating chirality.
- Synthesis of a new β-amino acid with a 3-deoxy-L-ara furnaoside side chain: the influence of the side chain on the conformation of α/β-peptides.
- Design and synthesis of peptides with hybrid helix-turn-helix (HTH) motif and their conformational study.
- New Class of Heterogeneous Helical Peptidomimetics.
- 12/14/14-Helix Formation in 2:1 α/β-Hybrid Peptides Containing Bicyclo[2.2.2]octane Ring Constraints.
- Helical α/β-depsipeptides with alternating residue types: conformational change from the 11-helix to the 14/15-helix.
- Helices with additional H‐bonds: crystallographic conformations of α,γ‐hybrid peptides helices composed of β‐hydroxy γ‐amino acids (statines)
- Diastereoselective synthesis of furanose and pyranose substituted glycine and alanine derivatives via proline-catalyzed asymmetric α-amination of aldehydes.
- Synthesis and conformational studies of short mixed γ/α-glycopeptides based on sugar γ3,3-amino acids
- Synthesis of β3-amino acid and peptides from D-ribose
- Synthesis of new 1,2-dideoxy C-linked carbo-β-amino acids and α/β-peptides with 11/9-helix, helix-turn and helix-turn-helix structures
- Synthesis and antiviral activity of some imidazo[1,2-b][1,3,4]thiadiazole carbohydrate derivatives.
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