Single-molecule force spectroscopy of polycystic kidney disease proteins.

Guillaume Foret · Methods in molecular biology · 2012

Summary

Protein engineering strategies and single-molecule AFM techniques for probing protein mechanics, with special emphasis on polycystic kidney disease (PKD) proteins are described and step-by-step protocols for preparing proteins and performing single-mite force measurements are provided.

Type: dissertation
Published: 2012-01-01
Cited by: 2
References: 32
DOI: https://doi.org/10.1007/978-1-61779-806-1_16
PubMed: https://pubmed.ncbi.nlm.nih.gov/22573448/
OpenAlex: https://openalex.org/W22573448
Semantic Scholar: https://api.semanticscholar.org/CorpusID:38049404

Keywords

Humanities, Segmentation, Computer science, Artificial intelligence, Art

References

Biophysical investigations of engineered polyproteins: implications for force data.Mercedes García — 2005
The remarkable mechanical strength of polycystin-1 supports a direct role in mechanotransduction.Thomas Frank — 2005
Point mutations alter the mechanical stability of immunoglobulin modulesJulio M. Fernández, Hongbin Li, Mariano Carrión‐Vázquez — 2000
New frontiers in atomic force microscopy: analyzing interactions from single-molecules to cells.Daniel J. Müller, Michael Krieg, David Alsteens — 2009
What can atomic force microscopy tell us about protein folding?Robert B. Best, Jane Clarke — 2002
Sensing specific molecular interactions with the atomic force microscopeErnst‐Ludwig Florin, Matthias Rief, Horst Lehmann — 1995
Pulling single molecules of titin by AFM—recent advances and physiological implicationsWolfgang A. Linke, Anika Grützner — 2008
Statistical mechanics of supercoiled DNA.John F. Marko, Eric D. Siggia — 1995
Stretching single molecules along unbinding and unfolding pathways with the scanning force microscope.Bruno Samorı̀ — 2000
Removal of the MDCK Cell Primary Cilium Abolishes Flow SensingHelle A. Prætorius, K. R. Spring — 2003
Force spectroscopy of single biomolecules.Matthias Rief, Helmut Grubmüller — 2002
Mechanotransduction gone awryDiana E. Jaalouk, Jan Lammerding — 2009
The micro‐mechanics of single molecules studied with atomic force microscopyThomas E. Fisher, Piotr E. Marszałek, Andrés F. Oberhauser — 1999
Mechanical Biochemistry of Proteins One Molecule at a Time*Andrés F. Oberhauser, Mariano Carrión‐Vázquez — 2008
Homocysteine-mediated reactivity and assembly of gold nanoparticles.I-Im S. Lim, Wui Ip, Elizabeth Crew — 2007
Bending the MDCK Cell Primary Cilium Increases Intracellular CalciumHelle A. Prætorius, K. R. Spring — 2001
Biomechanics, One Molecule at a Time*Amit Mehta, Matthias Rief, James A. Spudich — 1999
Entropic elasticity of lambda-phage DNA.Carlos Bustamante, John F. Marko, Eric D. Siggia — 1994
Atomic force microscopy: mechanical unfolding of proteins.Ross W.S. Rounsevell — 2004
Silanized surfaces for in vitro studies of actomyosin function and nanotechnology applications.Mark Sundberg, Jenny Rosengren-Holmberg, Richard Bunk — 2003

Cited by

UNC-45B chaperone: the role of its domains in the interaction with the myosin motor domain.Paul J. Bujalowski, Paul Nicholls, Andrés F. Oberhauser — 2014
Tracking Unfolding and Refolding Reactions of Single Proteins using Atomic Force Microscopy MethodsPaul J. Bujalowski, Andrés F. Oberhauser — 2013

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