Nutrient restriction during early life reduces cell proliferation in the hippocampus at adulthood but does not impair the neuronal differentiation process of the new generated cells.
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Summary
The results indicate that the decreased number of hippocampal neurons in perinatally undernourished rats is due to the deleterious effects of early nutrient restriction on cell proliferation but not on the neuronal differentiation process of the new generated cells.
- Type
- article
- Published
- 2011-11-24
- Cited by
- 47
- References
- 50
- OpenAlex
- https://openalex.org/W21930191
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:26106874
Keywords
Humanities, Art
References
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- The implication of protein malnutrition on cardiovascular control systems in rats
- Perinatal malnutrition stimulates motivation through reward and enhances drd(1a) receptor expression in the ventral striatum of adult mice.
- Effects of chronic malnourishment and aging on the ultrastructure of pyramidal cells of the dorsal hippocampus
- Nutritionally Driven Differential Gene Expression Leads to Heterochronic Brain Development in Honeybee Castes
- Malnutrition alters the cardiovascular responses induced by central injection of tityustoxin in Fischer rats.
- Early postnatal protein malnutrition impairs recognition memory in rats (Rattus norvegicus)
- The interplay of early-life stress, nutrition, and immune activation programs adult hippocampal structure and function
- Effects of protein restriction during gestation and lactation on cell proliferation in the hippocampus and subventricular zone: functional implications. Protein restriction alters hippocampal/SVZ cell proliferation.
- Effects of acute stress on learning and memory processes of malnourished rats
- Malnutrition and brain development: an analysis of the effects of inadequate diet during different stages of life in rat.
- Adult Neurogenesis and Mental Illness
- Impact of taurine supplementation on blood pressure in gestational protein-restricted offspring: Effect on the medial solitary tract nucleus cell numbers, angiotensin receptors, and renal sodium handling
- Protein Content and Methyl Donors in Maternal Diet Interact to Influence the Proliferation Rate and Cell Fate of Neural Stem Cells in Rat Hippocampus
- Perinatal programming of adult hippocampal structure and function; emerging roles of stress, nutrition and epigenetics.
- Mid‐ to late term hypoxia in the mouse alters placental morphology, glucocorticoid regulatory pathways and nutrient transporters in a sex‐specific manner
- Programming of hippocampal structure and function by early-life stress: Opportunities for nutritional intervention
- Early malnutrition results in long-lasting impairments in pattern-separation for overlapping novel object and novel location memories and reduced hippocampal neurogenesis
- Altered gene expression in hippocampus and depressive‐like behavior in young adult female mice by early protein malnutrition
- Early-Life Nutritional Programming of Cognition-The Fundamental Role of Epigenetic Mechanisms in Mediating the Relation between Early-Life Environment and Learning and Memory Process.
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