Detection of apoptotic circulating tumor cells in advanced pancreatic cancer following 5-fluorouracil chemotherapy
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Summary
Punctate, granular, and bubble-like morphologies with CA19-9 and CK8/18 staining were found and may reflect apoptosis in pancreatic cancer cells and CTCs, which may indicate the efficacy of chemotherapy in Pancic cancer patients.
- Type
- article
- Published
- 2011-10-15
- Cited by
- 62
- References
- 30
- Access
- Open access
- OpenAlex
- https://openalex.org/W1964763549
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:31011525
Keywords
Pancreatic cancer, Circulating tumor cell, Chemotherapy, Medicine, Cancer
References
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- Overexpression of Bax sensitizes human pancreatic cancer cells to apoptosis induced by chemotherapeutic agents
- Eradication of EGFR-positive circulating tumor cells and objective tumor response with lapatinib and capecitabine
- Quantitative real‐time RT‐PCR for detection of disseminated tumor cells in peripheral blood of patients with colorectal cancer using different mRNA markers
- Apoptosis of circulating tumor cells in prostate cancer patients
- Detection of circulating tumor cells: Clinical relevance of a novel metastatic tumor marker.
- Current diagnosis and treatment of pancreatic cancer in China.
- Case study of the morphologic variation of circulating tumor cells.
- Caspase Cleavage of Keratin 18 and Reorganization of Intermediate Filaments during Epithelial Cell Apoptosis
- E-cadherin regulates metastasis of pancreatic cancer in vivo and is suppressed by a SNAIL/HDAC1/HDAC2 repressor complex.
- Preliminary Investigation of the Clinical Significance of Detecting Circulating Tumor Cells Enriched from Lung Cancer Patients
- Circulating breast cancer cells are frequently apoptotic.
- Colorectal carcinoma antigens detected by hybridoma antibodies
- Comparison of Plasma Tu-M2-PK and CA19-9 in Pancreatic Cancer
Cited by
- Improving pancreatic cancer diagnosis using circulating tumor cells: prospects for staging and single-cell analysis
- Pharmacogenetics in pancreatic cancer.
- Reduced dissemination of circulating tumor cells with no-touch isolation surgical technique in patients with pancreatic cancer.
- Increased plasma microRNA and CD133/CK18-positive cancer cells in the pleural fluid of a pancreatic cancer patient with liver and pleural metastases and correlation with chemoresistance.
- Validation of a multiparameter flow cytometry method for the determination of phosphorylated extracellular‐signal‐regulated kinase and DNA in circulating tumor cells
- Is the detection of circulating tumor cells in locally advanced pancreatic cancer a useful prognostic marker?
- Early diagnosis of pancreatic cancer: challenges and new developments
- Circulating tumor cells in pancreatic cancer patients: enrichment and cultivation.
- Circulating tumor cells in pancreatic cancer patients: Methods of detection and clinical implications
- Detection and molecular analysis of circulating tumor cells for early diagnosis of pancreatic cancer.
- Circulating tumor cells in breast cancer beyond the genotype of primary tumor for tailored therapy
- Circulating tumor cells in gastrointestinal malignancies
- Clinical applications of circulating tumor DNA and circulating tumor cells in pancreatic cancer
- Prognostic Significance of MUC-1 in Circulating Tumor Cells in Patients With Metastatic Pancreatic Adenocarcinoma
- Available technologies and clinical applications of targeted chemotherapy in pancreatic cancer.
- Circulating and disseminated tumour cells as potential biomarkers for treatment response and disease progression in patients with locally advanced and/or metastatic pancreatic cancer
- Circulating Tumor Cells in Gastrointestinal Cancer: Current Practices and Future Directions.
- Pancreatic cancer: Are "liquid biopsies" ready for prime-time?
- Single-cell genomic analysis of head and neck squamous cell carcinoma
- Circulating Tumor Cells as a Biomarker in Pancreatic Ductal Adenocarcinoma
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