Classically and alternatively activated bone marrow derived macrophages differ in cytoskeletal functions and migration towards specific CNS cell types
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Summary
It is shown that bone marrow derived CA and AA macrophages have a distinct migratory capacity towards medium conditioned by various cell types of the CNS, and are prone to migrate towards neurons in the CNS.
- Type
- article
- Published
- 2011-05-26
- Cited by
- 109
- References
- 87
- Access
- Open access
- OpenAlex
- https://openalex.org/W2165155335
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:14114360
Keywords
Cell biology, Macrophage, RHOA, Podosome, Phagocytosis
References
- Activated macrophage/microglial cells can promote the regeneration of sensory axons into the injured spinal cord.
- Effects of naturally occurring flavonoids on nitric oxide production in the macrophage cell line RAW 264.7 and their structure-activity relationships.
- Temporal expression of different pathways of 1-arginine metabolism in healing wounds.
- Localization of monocyte chemoattractant peptide-1 expression in the central nervous system in experimental autoimmune encephalomyelitis and trauma in the rat.
- Transcriptional Profiling of the Human Monocyte-to-Macrophage Differentiation and Polarization: New Molecules and Patterns of Gene Expression1
- Expression of monocyte chemoattractant protein-1 and other beta-chemokines by resident glia and inflammatory cells in multiple sclerosis lesions.
- Treatment of an Infected Murine Macrophage Cell Line (J774A.1) with Interferon-γ but Not Tumor Necrosis Factor-α or Live Mycobacterium intracellulare Alone Modulates the Expression of Adhesion Molecules
- A combination immunomodulatory treatment promotes neuroprotection and locomotor recovery after contusion SCI.
- Tumor-associated macrophages and the related myeloid-derived suppressor cells as a paradigm of the diversity of macrophage activation.
- Reciprocal regulation of the nitric oxide synthase/arginase balance in mouse bone marrow‐derived macrophages by TH 1 and TH 2 cytokines
- Macrophages of multiple sclerosis patients display deficient SHP-1 expression and enhanced inflammatory phenotype
- Inhibitory effect of luteolin on osteoclast differentiation and function
- Macrophage phagocytosis of myelin in vitro determined by flow cytometry: phagocytosis is mediated by CR3 and induces production of tumor necrosis factor-alpha and nitric oxide.
- Tumour necrosis factor alpha mRNA expression in early multiple sclerosis lesions: Correlation with demyelinating activity and oligodendrocyte pathology
- Type II monocytes modulate T cell–mediated central nervous system autoimmune disease
- Transfused Macrophages Ameliorate Pancreatic and Renal Injury in Murine Diabetes Mellitus
- Specific inflammatory cytokines regulate the expression of human monocyte 15-lipoxygenase.
- Differences in angiogenic potential of classically vs alternatively activated macrophages.
- Neurological disability correlates with spinal cord axonal loss and reduced N‐acetyl aspartate in chronic multiple sclerosis patients
- The Expression of Tissue‐type Plasminogen Activator, Matrix Metalloproteases and Endogenous Inhibitors in the Central Nervous System in Multiple Sclerosis: Comparison of Stages in Lesion Evolution
Cited by
- Polarisation et rôle des macrophages dans des contextes inflammatoires aigus et chroniques
- Role of alveolar epithelial cells in macrophage responses against mycobacterial infections
- Erythropoietin upregulates growth associated protein-43 expression and promotes retinal ganglion cell axonal regeneration in vivo after optic nerve crush
- Essential Role of Lysophosphatidylcholine Acyltransferase 3 in the Induction of Macrophage Polarization in PMA‐Treated U937 Cells
- Human macrophage polarization in vitro: maturation and activation methods compared.
- Alternatively Activated Macrophages in Spinal Cord Injury and Remission: Another Mechanism for Repair?
- Adoptive transfer of M2 macrophages promotes locomotor recovery in adult rats after spinal cord injury.
- Erythropoietin promotes axonal regeneration after optic nerve crush in vivo by inhibition of RhoA/ROCK signaling pathway.
- CSF-1R Signaling in Health and Disease: A Focus on the Mammary Gland
- SDF-1/CXCL12: its role in spinal cord injury.
- Macrophage Control of Phagocytosed Mycobacteria Is Increased by Factors Secreted by Alveolar Epithelial Cells through Nitric Oxide Independent Mechanisms
- Development of skin inflammation test model by co-culture of reconstituted 3D skin and RAW264.7 cells
- The thyroid hormone triiodothyronine controls macrophage maturation and functions: protective role during inflammation.
- Regulation of Macrophage Motility by the Water Channel Aquaporin-1: Crucial Role of M0/M2 Phenotype Switch
- Blood leukocytes and macrophages of various phenotypes have distinct abilities to form podosomes and to migrate in 3D environments.
- Divergent results induced by different types of septic shock in transglutaminase 2 knockout mice
- Glial hemichannels and their involvement in aging and neurodegenerative diseases
- Function of microglia and macrophages in secondary damage after spinal cord injury
- Physical and mechanical regulation of macrophage phenotype and function
- Macrophage/Microglia Plasticity in Multiple Sclerosis
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