Subchronic administration of Catha edulis F. (khat) extract is marked by elevation of cardiac biomarkers and subendocardial necrosis besides blood pressure alteration in rats.
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Summary
Findings collectively indicate that the high dose of crude khat extract modulated most of the hemodynamic, biochemical and histopathological parameters in rats and hence chronic use of khat at higher dose and for longer sessions bear a significant risk for cardiovascular morbidities.
- Type
- article
- Published
- 2011-06-14
- Cited by
- 25
- References
- 48
- OpenAlex
- https://openalex.org/W2043274128
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:41769063
Keywords
Khat, Medicine, Blood pressure, Stimulant, Dosing
References
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- Cardiac markers and their point-of-care testing for diagnosis of acute myocardial infarction.
- Khat rings twice: Khat-induced thrombosis in two vascular territories
Cited by
- A PRELIMINARY STUDY ON THE EFFECTS OF KHAT (Catha edulis) ON LIVER AND KIDNEY OF MICE
- Tumor-targeted paclitaxel delivery and enhanced penetration using TAT-decorated liposomes comprising redox-responsive poly(ethylene glycol).
- Subacute administration of crude khat (Catha edulis F.) extract induces mild to moderate nephrotoxicity in rats
- Toxicological Features of Catha edulis (Khat) on Livers and Kidneys of Male and Female Sprague-Dawley Rats: A Subchronic Study
- Cardiovascular complications of Khat.
- [Acute myocardial infarction in Djibouti: 2-year prospective study].
- Evaluation of the reversibility and possible mechanisms of antifertility of Catha edulis F. (khat) extract following subacute administration in rodents
- Before the ban - an exploratory study of a local khat market in East London, U.K
- Overview of literature and information on "khat-related" mortality: a call for recognition of the issue and further research.
- Conflicting reports on the role of the glycemic effect of Catha edulis (Khat): A systematic review and meta-analysis.
- Subchronic oral administration of crude khat extract (Catha edulis forsk) induces schizophernic-like symptoms in mice
- Behavioral evidence for the interaction between cannabinoids and Catha edulis F. (Khat) in mice.
- Pharmacological and Toxicological Effects of Catha edulis F. (Khat)
- Biochemical, hormonal and toxicological effects of catha edulis (khat) on pregnancy and fetal development in olive Baboons (papio anubis)
- Effect of Catha edulis (khat) on pancreatic functions in streptozotocin-induced diabetes in male Sprague-Dawley rats
- Analysis of cathinone and cathine in urine sample of khat chewer presenting with hemorrhagic stroke
- Involvement of CB2 Receptors in the Neurobehavioral Effects of Catha Edulis (Vahl) Endl. (Khat) in Mice
- The impact of catha edulis (vahl) forssk. ex endl. (celestraceae) (khat) on pharmacokinetics of clinically used drugs
- A comprehensive bibliometric analysis of Catha edulis (Vahl) Endli (Khat) research (1961–2021)
- EVALUATION OF CARDIOPROTECTIVE EFFECT OF DAIDZEIN IN 5-FLUOROURACIL-INDUCED CARDIOTOXICITY IN WISTAR RATS
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