Side-by-Side Comparison of Five Commercial Media Systems in a Mouse Model: Suboptimal In Vitro Culture Interferes with Imprint Maintenance1

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Summary

Comparing side-by-side comparisons of five commercial embryo culture systems shows that embryo culture in all commercial media systems resulted in imprinted methylation loss compared to in vivo-derived embryos, although some media systems were able to maintain imprintedmethylation levels more similar to those of in vitro embryos in comparison to embryos cultured in Whitten medium.

Type
dissertation
Published
2010-12-01
Cited by
154
References
69
Access
Open access

Keywords

Humanities, Multicast, Computer science, Art, Computer network

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