Respiratory and cardiovascular effects of metals in ambient particulate matter: a critical review.

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Summary

The in vivo and in vitro studies reviewed provide indications that the probable mechanisms involved in the respiratory and cardiac effects from high metal exposures include: an inflammatory response mediated by formation of ROS, upregulation of genes coding for inflammatory cytokines, altered expression of genes involved in cell signaling pathways and maintenance of metals homeostasis.

Type
review
Published
2015-01-01
Cited by
49
References
112

Keywords

Particulates, Air quality index, Environmental health, Environmental science, Respiratory system

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