RNA-seq: from technology to biology

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Summary

Technical issues accompanying RNA-seq data generation and analysis are described, highlighting differences to array-based approaches and recent biological insight gained from applyingRNA-seq and related approaches to deeply sample transcriptomes in different cell types or physiological conditions are reviewed.

Type
review
Published
2009-10-27
Cited by
561
References
111
Access
Open access

Keywords

Computational biology, Biology, Transcriptome, RNA-Seq, RNA

References

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