Role of autophagy and autophagy genes in inflammatory bowel disease.
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Summary
This chapter reviews the recent literature on the roles of ATG16L1 and IRGM1 in the autophagy pathway, inflammation, antimicrobial immunity, and the biology of the intestine, and discusses how these genes may contribute to Crohn's disease pathogenesis.
- Type
- article
- Published
- 2009-01-01
- Cited by
- 56
- References
- 107
- OpenAlex
- https://openalex.org/W19802564
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:5344537
Keywords
Nat, Operating system, Computer science, Unix, Programming language
References
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Cited by
- Biological pathways involved in the development of inflammatory bowel disease
- Repercussões bucais de doenças gastrointestinais de pacientes dos Serviços de Gastroenterologia e Endoscopia do HU/UFSC
- Viruses in Rodent Colonies: Lessons Learned from Murine Norovirus
- Intestinal inhibition of Atg7 prevents tumour initiation through a microbiome-influenced immune response and suppresses tumour growth
- [Barrier- and autophagic functions of the intestinal epithelia: role of disturbances in the pathogenesis of Crohn's disease].
- Molecular characterization of LC3-associated phagocytosis (LAP) reveals distinct roles for Rubicon, NOX2, and autophagy proteins
- AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
- Enterocyte death and intestinal barrier maintenance in homeostasis and disease.
- T-cell selection and intestinal homeostasis
- The universe of immune deficiencies in Crohn's disease: a new viewpoint for an old disease?
- Intestinal Macrophages and Response to Microbial Encroachment
- Carbohydrate Elimination or Adaptation Diet for Symptoms of Intestinal Discomfort in IBD: Rationales for “Gibsons' Conundrum”
- Crucial role for autophagy in degranulation of mast cells.
- Biogenesis and cargo selectivity of autophagosomes.
- Loss of autophagy causes a synthetic lethal deficiency in DNA repair
- Analysis of macroautophagy by immunohistochemistry
- Altered autophagic flux enhances inflammatory responses during inflammation-induced preterm labor
- Autophagy in immunity
- Ubiquitin-like proteins and autophagy at a glance
- The Impact of Genomics on Pediatric Research and Medicine
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