PinX1 Is a Novel Microtubule-binding Protein Essential for Accurate Chromosome Segregation*

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Summary

The real time imaging analyses show that suppression of PinX1 by small interference RNA abrogates faithful chromosome segregation and results in anaphase chromatid bridges in mitosis and micronuclei in interphase, suggesting an essential role of Pin X1 in chromosome stability.

Type
article
Published
2009-06-24
Cited by
48
References
42

Keywords

Philosophy

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