Postinjury multiple organ failure.
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Summary
The essential MOF-related terminology is defined, the changing epidemiology of MOF is summarized, the current understanding of the pathophysiology is described, the available strategies for prevention/treatment based on the identified independent predictors are discussed and future directions for research are provided.
- Type
- review
- Published
- 2009-09-01
- Cited by
- 294
- References
- 56
- Access
- Open access
- OpenAlex
- https://openalex.org/W2072398380
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:44939608
Keywords
Epidemiology, Intensive care medicine, Medicine, Intensive care unit, Terminology
References
- A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group.
- Effect of intestinal lymphatic circulation blockage in two-hit rats.
- Multiple Organ Failure
- The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure
- Allogenic Blood Transfusion in the First 24 Hours after Trauma Is Associated with Increased Systemic Inflammatory Response Syndrome (SIRS) and Death
- The Abdominal Compartment Syndrome as a Second Insult During Systemic Neutrophil Priming Provokes Multiple Organ Injury
- Multiple system organ failure. The role of uncontrolled infection.
- Multiple organ dysfunction during resuscitation is not postinjury multiple organ failure.
- Continuous muscle tissue oxygenation in critically injured patients: a prospective observational study.
- Alteration of the postinjury hyperinflammatory response by means of resuscitation with a red cell substitute.
- Early hyperglycemia predicts multiple organ failure and mortality but not infection.
- Prognosis in Acute Organ‐System Failure
- Synbiotics, prebiotics, glutamine, or peptide in early enteral nutrition: a randomized study in trauma patients.
- Early neutrophil sequestration after injury: a pathogenic mechanism for multiple organ failure.
- Postinjury multiple organ failure: a bimodal phenomenon.
- Postinjury life threatening coagulopathy: is 1:1 fresh frozen plasma:packed red blood cells the answer?
- Supranormal trauma resuscitation causes more cases of abdominal compartment syndrome.
- Multiple-organ failure. Generalized autodestructive inflammation?
- Early trauma polymorphonuclear neutrophil responses to chemokines are associated with development of sepsis, pneumonia, and organ failure.
- Multiple organ failure still a major cause of morbidity but not mortality in blunt multiple trauma.
Cited by
- Modulation of Inflammatory Response in Surgical Trauma
- DNA attenuates enterocyte Toll-like receptor 4-mediated intestinal mucosal injury after remote trauma.
- Notfallnarkose, Atemwegsmanagement und Beatmung beim Polytrauma
- Caspase-1 Is Hepatoprotective during Trauma and Hemorrhagic Shock by Reducing Liver Injury and Inflammation
- The Role of Damage-Associated Molecular Patterns (DAMPs) in Human Diseases: Part II: DAMPs as diagnostics, prognostics and therapeutics in clinical medicine.
- THE ROLE OF INFLAMMASOME AND CASPASE-1 IN REGULATING ADAPTIVE RESPONSE TO OXIDATIVE STRESS IN MOUSE HEPATOCYTES
- A “clean case” of systemic injury: Mesenteric lymph after hemorrhagic shock elicits a sterile inflammatory response
- Multiple Organ Failure
- Characterising factors predictive of infection in severely injured patients
- Novel Model of Peripheral Tissue Trauma Induced Inflammation and Gastrointestinal Dysmotility
- High incidence of post‐injury pneumonia in intensive care‐treated trauma patients
- Extracellular DNA and histones: double‐edged swords in immunothrombosis
- The epidemiology of multiple‐organ failure: a definition controversy
- Early predictors of morbidity and mortality in trauma patients treated in the intensive care unit
- Hip fracture aggravates systemic inflammation and lung injury in aged chronic cigarette smoke exposed rats
- The impact of surgical timing and intervention on outcome in traumatized dogs and cats.
- Up-to-date management of patients with blunt abdominal trauma
- Clinical features, complications and mortality in critically ill patients with 2009 influenza A(H1N1) in Sfax,Tunisia
- Hemorrhage-inducedIL-1R pathway in lung is suppressed by 3,5-bis(2-fluorobenzylidine)-4-piperidone (EF24) in a rat model of hypovolemic shock
- Validation of the Denver Emergency Department Trauma Organ Failure Score to Predict Post-Injury Multiple Organ Failure
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