Caenorhabditis elegans has a phosphoproteome atypical for metazoans that is enriched in developmental and sex determination proteins.
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Summary
High accuracy mass spectrometry and comprehensive bioinformatic analysis are applied to determine and characterize the in vivo Caenorhabditis elegans phosphoproteome for the first time and show that the C. elegans specific dosage complex can be phosphorylated on most subunits, suggesting its regulation by kinases.
- Type
- dissertation
- Published
- 2009-07-02
- Cited by
- 78
- References
- 61
- Access
- Open access
- OpenAlex
- https://openalex.org/W19530675
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:11089274
Keywords
Mathematics, Humanities, Brauer group, Pure mathematics, Philosophy
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Cited by
- A Compendium of Caenorhabditis elegans RNA Binding Proteins Predicts Extensive Regulation at Multiple Levels
- RIC-3 phosphorylation enables dual regulation of excitation and inhibition of Caenorhabditis elegans muscle
- Evidence for phosphorylation in the MSP cytoskeletal filaments of amoeboid spermatozoa.
- Cardioproteomics: advancing the discovery of signaling mechanisms involved in cardiovascular diseases.
- Histone H3 Ser57 and Thr58 phosphorylation in the brain of 5XFAD mice
- Prediction of Functionally Important Phospho-Regulatory Events in Xenopus laevis Oocytes
- Mass spectrometry‐driven phosphoproteomics: patterning the systems biology mosaic
- Comparison of phosphorylation patterns across eukaryotes by discriminative N-gram analysis
- Cyclin E and Cdk2 Control GLD-1, the Mitosis/Meiosis Decision, and Germline Stem Cells in Caenorhabditis elegans
- Enhanced FASP (eFASP) to Increase Proteome Coverage and Sample Recovery for Quantitative Proteomic Experiments
- Phosphoproteomic Analysis of Protein Phosphorylation Networks in Tetrahymena thermophila, a Model Single-celled Organism*
- Centrosome/Cell Cycle Uncoupling and Elimination in the Endoreduplicating Intestinal Cells of C. elegans
- Brain phosphoproteome obtained by a FASP-based method reveals plasma membrane protein topology.
- Comparison of ultrafiltration units for proteomic and N-glycoproteomic analysis by the filter-aided sample preparation method.
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- Strategies for the identification of kinase substrates using analog-sensitive kinases.
- Using proteomic strategies for sequencing and post-translational modifications assignment of antigen-5, a major allergen from the venom of the social wasp Polybia paulista.
- A worm rich in protein: Quantitative, differential, and global proteomics in Caenorhabditis elegans.
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