Antidiabetic effects of 11β‐HSD1 inhibition in a mouse model of combined diabetes, dyslipidaemia and atherosclerosis

Keywords

Mandate, Business, Agency (philosophy), Political science, Compliance (psychology)

References

• Glucocorticoids in adipocytes stimulate visceral obesity.George Wolf — 2002
• Anti-inflammatory actions of glucocorticoids: molecular mechanisms.Peter J. Barnes — 1998
• Structural Characterization and Pharmacodynamic Effects of an Orally Active 11β‐Hydroxysteroid Dehydrogenase Type 1 InhibitorClarence Hale, Murielle M. Véniant, Zhulun Wang — 2007
• Drug therapy of the metabolic syndrome: minimizing the emerging crisis in polypharmacyScott M. Grundy — 2006
• Selective inhibition of 11 beta-hydroxysteroid dehydrogenase type 1 improves hepatic insulin sensitivity in hyperglycemic mice strains.Pēteris Alberts, Cecilia Nilsson, Göran Selén — 2003
• Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 as a promising therapeutic target.Małgorzata Wamil, J. R. Seckl — 2007
• Time of the day for 11β‐HSD1 inhibition plays a role in improving glucose homeostasis in DIO miceMurielle M. Véniant, Clarence Hale, Renée Komorowski — 2009
• Localization of 2 11beta-OH steroid dehydrogenase isoforms in aortic endothelial cells.Andrew S. Brem, Robert B. Bina, Thomas C. King — 1998
• The role of tyrosine 177 in human 11beta-hydroxysteroid dehydrogenase type 1 in substrate and inhibitor binding: an unlikely hydrogen bond donor for the substrate.Ki Won Kim, Zhulun Wang, James Busby — 2006
• Inflammation and Atherosclerosis: Novel Insights Into Plaque Formation and DestabilizationGuido Stoll, Martin Bendszus — 2006
• Peroxisome proliferator-activated receptor-gamma ligands inhibit adipocyte 11beta -hydroxysteroid dehydrogenase type 1 expression and activity.Joel P. Berger, Michael Tanen, Alex Elbrecht — 2001
• Preadipocyte 11beta-hydroxysteroid dehydrogenase type 1 is a keto-reductase and contributes to diet-induced visceral obesity in vivo.Ricardo De Sousa Peixoto, Sophie Turban, Jenny Helen Battle — 2008
• Cortisol, 11 beta-hydroxysteroid dehydrogenase type 1 and central obesity.Paul M. Stewart, Jeremy Tomlinson — 2002
• Induction of 11beta-hydroxysteroid dehydrogenase type 1 but not -2 in human aortic smooth muscle cells by inflammatory stimuli.Tian‐Quan Cai, Birming Wong, Steven S. Mundt — 2001
• Tissue-specific dysregulation of cortisol metabolism in human obesity.Eva Rask, Tommy Olsson, Stefan Söderberg — 2001
• Intra-vascular glucocorticoid metabolism as a modulator of vascular structure and functionPatrick W. F. Hadoke, L. J. Macdonald, James J. Logie — 2006
• The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men.Hanna‐Maaria Lakka — 2002
• Development of 11beta-HSD1 inhibitors for the treatment of type 2 diabetes.Clarence Hale, Minghan Wang — 2008
• Dissociation between the insulin-sensitizing effect of rosiglitazone and its effect on hepatic and intestinal lipoprotein production.Hélène Duez, Benoı̂t Lamarche, Kristine D. Uffelman — 2008
• Inhibition of 11β-hydroxysteroid dehydrogenase type 1 reduces food intake and weight gain but maintains energy expenditure in diet-induced obese miceS. J. Y. Wang, Susan Birtles, J. de Schoolmeester — 2006

Cited by

• Rôle de l’enzyme 11β-hydroxystéroïde-déshydrogénase de type 1 dans le risque métabolique associé à l’obésitéA Iovino, Nicolas Paquot, André Scheen — 2009
• Role of intra-cellular glucocorticoid regulation in vascular lesion developmentJavaid Iqbal — 2010
• 11β-hydroxysteroid dehydrogenase type 1 : a new therapeutic target post-myocardial infarction?Sara J. McSweeney — 2010
• La 11β-hydroxystéroïde déshydrogénase de type 1 – 1re partieA Iovino, André Scheen — 2009
• Continuous inhibition of 11β‐hydroxysteroid dehydrogenase type I in adipose tissue leads to tachyphylaxis in humans and rats but not in micePablo Morentin Gutierrez, Amy Gyte, Joanne deSchoolmeester — 2015
• Metabolic syndrome components in murine modelsHeather A. Lawson, James M. Cheverud — 2010
• Is metabolic syndrome a mild form of Cushing’s syndrome?Armand Krikorian, Mehreen Ali Khan — 2010
• Study of the Effects of Monacolin K and Other Constituents of Red Yeast Rice on Obesity, Insulin-Resistance, Hyperlipidemia, and Nonalcoholic Steatohepatitis Using a Mouse Model of Metabolic SyndromeMakoto Fujimoto, Koichi Tsuneyama, Shao‐Yuan Chen — 2012
• Genome-Wide Analysis of Glucocorticoid Receptor Binding Regions in Adipocytes Reveal Gene Network Involved in Triglyceride HomeostasisChi-Yi Yu, Oleg Mayba, Joyce V. Lee — 2010
• Age-Dependent Rescue by Simvastatin of Alzheimer's Disease Cerebrovascular and Memory DeficitsXin‐Kang Tong, Clotilde Lecrux, Édith Hamel — 2012
• 11β‐Hydroxysteroid dehydrogenase type 1: relevance of its modulation in the pathophysiology of obesity, the metabolic syndrome and type 2 diabetes mellitusCidália Pereira, Isabel Azevedo, Rosário Monteiro — 2012
• Antisense reduction of 11β-hydroxysteroid dehydrogenase type 1 enhances energy expenditure, and insulin sensitivity independent of food intake in C57BL/6J mice on a Western-type dietGuoping Li, Antonio Hernández‐Ono, Rosanne M. Crooke — 2011
• 11β-hydroxysteroid dehydrogenase type 1 deficiency in bone marrow-derived cells reduces atherosclerosisTiina Kipari, Patrick W. F. Hadoke, Javaid Iqbal — 2013
• 11β-Hydroxysteroid dehydrogenase type 1 inhibitors for the treatment of type 2 diabetesStuart Morgan, Jeremy Tomlinson — 2010
• Exercise ameliorates high-fat diet-induced metabolic and vascular dysfunction, and increases adipocyte progenitor cell population in brown adipose tissue.Xiaohua Xu, Zhekang Ying, Ming Cai — 2011
• Contribution of endogenous glucocorticoids and their intra-vascular metabolism by 11β-HSDs to post-angioplasty neointimal proliferation in miceJavaid Iqbal, Linsay J. Macdonald, Lucinda Low — 2012
• Targeting the pre-receptor metabolism of cortisol as a novel therapy in obesity and diabetes.Laura Gathercole, Paul M. Stewart — 2010
• Modulation of 11β-Hydroxysteroid Dehydrogenase Type 1 Activity by 1,5-Substituted 1H-TetrazolesScott P. Webster, Margaret Binnie, Kirsty M.M. McConnell — 2010
• Effects of antisense-mediated inhibition of 11β-hydroxysteroid dehydrogenase type 1 on hepatic lipid metabolism[S]Guoping Li, Antonio Hernández‐Ono, Rosanne M. Crooke — 2011
• Acute Inhibition of 11β-Hydroxysteroid Dehydrogenase Type-1 Improves Memory in Rodent Models of CognitionEric G. Mohler, Kaitlin E. Browman, Victoria A. Roderwald — 2011

Related papers

• Should New CRA Have "Tolerance for Ambiguity"?Griffith L. Garwood — 1997
• Countdown to the New CRAJo Ann S. Barefoot — 1995
• Don't Dismiss CRA Strategic Plan OptionJo Ann S. Barefoot — 1995
• It's Time to Trade in Your Compliance ProgramJo Ann S. Barefoot — 1995
• How Do You Earn a Place at the Table? You Have to Join the Team While Helping the Bank Play by the RulesLyn Farrell — 2014
• The Association between Serum Matricellular Protein: Secreted Protein Acidic and Rich in Cysteine-Like 1 Levels and Ischemic Stroke Severity.Leslie Callaway, Mark Kruhm — 2017
• Is That Loan Really CollateralizedCatherine D. Meyer — 2001
• In a Tax Practice, Everything Is Fine, until It's Not!Charles P. Rettig — 2016
• How Does a Community Bank Compliance Officer Cope? 12 Strategies and Tips for SurvivalAna M. Foster — 2014