Proteomics analyses reveal the evolutionary conservation and divergence of N-terminal acetyltransferases from yeast and humans
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Summary
Although the COmbined FRActional DIagonal Chromatography technology was used to determine the N-terminal acetylation status of 742 human and yeast protein N termini, it was revealed that NatA from humans and yeast have identical or nearly identical specificities.
- Type
- article
- Published
- 2009-05-19
- Cited by
- 547
- References
- 25
- Access
- Open access
- OpenAlex
- https://openalex.org/W19420222
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:28602766
Keywords
Environmental science
References
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- Mechanistic insight into taxol-induced cell death
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- Importance of the Sir3 N Terminus and Its Acetylation for Yeast Transcriptional Silencing
Cited by
- TopFIND, a knowledgebase linking protein termini with function
- Co-expression for intracellular processing in microbial protein production
- A Saccharomyces cerevisiae Model Reveals In Vivo Functional Impairment of the Ogden Syndrome N-Terminal Acetyltransferase NAA10 Ser37Pro Mutant*
- Positional proteomics reveals differences in N‐terminal proteoform stability
- N-Alpha-Acetyltransferases and Regulation of CFTR Expression
- Crystal structure of the Golgi-associated human N-alpha acetyltransferase 60 reveals the molecular determinants for substrate-specific acetylation
- The intrinsic disorder alphabet. III. Dual personality of serine
- Omics Assisted N-terminal Proteoform and Protein Expression Profiling On Methionine Aminopeptidase 1 (MetAP1) Deletion*
- Three decades of studies to understand the functions of the ubiquitin family.
- Understanding the Posttranslational Regulation of the Response Regulator Rcsb and Acetyl Phosphate as an Acetyl Group Donor in E. Coli
- Production of amino-terminally acetylated recombinant proteins in E. coli
- In-gel N-acetylation for the quantification of the degree of protein in vivo N-terminal acetylation.
- Nouvelles méthodologies protéomiques d’aide à l’annotation des génomes et à la validation des séquences protéiques
- Approaches for Improved Positional Proteomics
- HPLC-based quantification of in vitro N-terminal acetylation.
- Molecular, cellular, and physiological significance of N-terminal acetylation.
- Neglected Tropical Diseases and Omics Science: Proteogenomics Analysis of the Promastigote Stage of Leishmania major Parasite
- Germline Development
- Heterologous expression of membrane proteins in Saccharomyces cerevisiae
- Analyse intégrative du rôle de l’excision de la méthionine N-terminale dans le cytoplasme des eucaryotes supérieurs
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