Recombinant DNA Vaccine Against Inhibition of Neurite Outgrowth Promotes Functional Recovery Associated with Endogeous NGF Expression in Spinal Cord Hemisected Adult Rats
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Summary
Results indicated that functional recovery in immunized rats could be correlated with endogeous NGF expression in hemisected rat spinal cords, and recombinant DNA vaccine encoding multiple domains significantly improved hindlimb locomotor functions in rats subjected to ablation of the dorsal halves of the cord.
- Type
- article
- Published
- 2009-04-01
- Cited by
- 3
- References
- 32
- OpenAlex
- https://openalex.org/W19337830
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:23770223
Keywords
Computer science
References
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- Slowed recovery of rod photoresponse in mice lacking the GTPase accelerating protein RGS9-1
- Axon regeneration in young adult mice lacking Nogo-A/B.
- Immunization with recombinant Nogo-66 receptor (NgR) promotes axonal regeneration and recovery of function after spinal cord injury in rats.
- Recombinant DNA vaccine encoding multiple domains related to inhibition of neurite outgrowth: a potential strategy for axonal regeneration
- Nogo-C is sufficient to delay nerve regeneration.
- Neurotrophin-3 enhances sprouting of corticospinal tract during development and after adult spinal cord lesion
- Identification of myelin-associated glycoprotein as a major myelin-derived inhibitor of neurite growth.
- A novel role for myelin-associated glycoprotein as an inhibitor of axonal regeneration.
- Early events in neurotrophin signalling via Trk and p75 receptors.
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Cited by
- Nerve growth factor improves functional recovery by inhibiting endoplasmic reticulum stress-induced neuronal apoptosis in rats with spinal cord injury
- Progress in Research on the Role of FGF in the Formation and Treatment of Corneal Neovascularization
- The Fibroblast Growth Factor Signaling Pathway in Metabolic Regulation, Development, Disease and Repair After Injury
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