The p53 Codon 72 Exon 4 BstUI Polymorphism and Endometrial Cancer in Caucasian Women
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Summary
The data did not demonstrate any significant difference in the prevalence of the p53 Arg72Pro genotype between patients and controls, providing evidence that this polymorphism is only weakly associated with the risk of endometrial cancer and prognostic factors in Caucasian women.
- Type
- article
- Published
- 2009-02-11
- Cited by
- 20
- References
- 40
- OpenAlex
- https://openalex.org/W19209008
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:23030006
Keywords
Medicine, Mesenchymal stem cell, Bone marrow, VEGF receptors, Cell biology
References
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- Cancer incidence and mortality in Europe
- p53 gene mutations are common in uterine serous carcinoma and occur early in their pathogenesis.
- Role of a p53 polymorphism in the development of human papilloma-virus-associated cancer
- p53 polymorphisms and haplotypes show distinct differences between major ethnic groups.
- p53 polymorphisms and haplotypes in different ethnic groups.
- Single nucleotide polymorphism: a new risk factor for endometrial cancer?
- Genotype, phenotype and cancer: Role of low penetrance genes and environment in tumour susceptibility
- p53 and p21 genetic polymorphisms and susceptibility to endometrial cancer.
- P53 codon 72 polymorphism and correlation with ovarian and endometrial cancer in Greek women
- Susceptibility to endometrial cancer: influence of allelism at p53, glutathione S-transferase (GSTM1 and GSTT1) and cytochrome P-450 (CYP1A1) loci.
- Association of p73 G4C14-to-A4T14 polymorphism at exon 2 and p53 Arg72Pro polymorphism with the risk of endometrial cancer in Japanese subjects.
- Two pathogenetic types of endometrial carcinoma.
- p53 in endometrial cancer and its putative precursors: evidence for diverse pathways of tumorigenesis.
- The polyproline region of p53 is required to activate apoptosis but not growth arrest
- Polymorphisms of the p53 gene in women with ovarian or endometrial carcinoma.
- The codon 72 polymorphic variants of p53 have markedly different apoptotic potential
- Trp53-dependent DNA-repair is affected by the codon 72 polymorphism
- World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs
Cited by
- TP53 Arg72Pro polymorphism and endometrial cancer risk: a meta-analysis
- Association of MDM2 and p53 Polymorphisms with the Advancement of Cervical Carcinoma
- Polymorphisms in promoter sequences of MDM2, p53, and p16INK4a genes in normal Japanese individuals
- Association of the p53 codon 72 polymorphism with clinicopathological characteristics of colorectal cancer through mRNA analysis.
- Evaluation of the p53 Arg72Pro polymorphism and its association with cancer risk: a HuGE review and meta-analysis.
- Meta-analysis of an association of codon 72 polymorphisms of the p53 gene with increased endometrial cancer risk.
- Association between p53 codon 72 polymorphism and cervical cancer risk among Asians: a HuGE review and meta-analysis.
- Lack of association between p53 codon 72 polymorphism and endometrial cancer: a meta-analysis.
- Polymorphism of p53 gene codon 72 in endometrial cancer: correlation with tumor grade and histological type.
- Absence of p53 gene mutations in exons 5 - 7 among breast cancer patients of Bengalee Hindu caste females, West Bengal, India.
- Association of the p53 codon 72 polymorphism with breast cancer in central part of Iran
- in normal Japanese individuals
- The association between codon72 polymorphism of p53 gene and the risk of endometrial cancer: an updating meta-analysis
- A p53 codon 72 polymorphism associated with breast cancer in Iranian patients
- TP53 codon 72 Arg/Arg polymorphism is associated with a higher risk for inflammatory bowel disease development.
- The Association Between p53 Codon 72 Polymorphism and Endometrial Cancer Risk: A System Review and Meta-analysis
- Meta-analysis of an association of codon 72 polymorphisms of the p 53 gene with increased endometrial cancer risk
- Association Between p 53 codon 72 Polymorphism and Cervical Cancer Risk Among Asians : a Huge Review and Meta-analysis
- Absence of P 53 Gene Mutations in Exons 5-7 Among Breast Cancer Patients of Bengalee Hindu Caste Females , West Bengal , India
- Association of TP53 [Arg72Pro] Gene Polymorphism and Breast Cancer Risk in Iraqi female patients
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