Structural characterization of the type-III pilot-secretin complex from Shigella flexneri.

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Summary

Using NMR spectroscopy, it is demonstrated that the C-terminal residues 553-570 of the Shigella flexneri secretin MxiD encompass the minimal binding domain for its cognate pilot MxiM, which establishes a framework for understanding the role of a pilot in the outer-membrane insertion and multimerization of the secretin ring.

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Published
2008-10-08
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