LESSONS FROM ONTARGET
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Summary
ONTARGET is the first trial to test the hypothesis of superiority of adding an ARB to an ACEi over the ACEi ramipril monotherapy in cardiovascular protection of the same broad range of high-risk patients, providing compelling evidence and clear answers to two important clinical questions.
- Type
- article
- Published
- 2008-05-01
- Cited by
- 3
- References
- 54
- OpenAlex
- https://openalex.org/W18714845
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:28200785
Keywords
Philosophy
References
- Prognostic relevance of atrial fibrillation in patients with chronic heart failure on long-term treatment with beta-blockers: results from COMET.
- Angiotensin receptors in the cardiovascular system.
- Interrupting the renin-angiotensin system: the role of angiotensin-converting enzyme inhibitors and angiotensin II receptor antagonists in the treatment of hypertension.
- Beyond blood pressure: new roles for angiotensin II
- The AT2 receptor--a matter of love and hate.
- The role of the renin-angiotensin system in the development of cardiovascular disease.
- Angiotensin‐II receptors: new targets for antihypertensive therapy
- The ONTARGET/TRANSCEND Trial Programme: baseline data
- The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report.
- The angiotensin II type 2 (AT2) receptor antagonizes the growth effects of the AT1 receptor: gain-of-function study using gene transfer.
- Angiotensin II Induces Hypertrophy, not Hyperplasia, of Cultured Rat Aortic Smooth Muscle Cells
- The cardiovascular continuum and renin–angiotensin–aldosterone system blockade
- Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the VALUE randomised trial.
- Diffuse craniospinal choroid plexus papilloma with involvement of both cerebellopontine angles
- Rationale for double renin-angiotensin-aldosterone system blockade.
- The global burden of chronic diseases: overcoming impediments to prevention and control.
- Angiotensin AT-1 receptor antagonism: complementary or alternative to ACE inhibition in cardiovascular and renal disease?
- Changes in skin angiotensin II receptors in rats during wound healing.
- Antihypertensive therapy in the presence of proteinuria.
- Angiotensin II-induced proliferation of aortic myocytes in spontaneously hypertensive rats.
Cited by
- ARE ACE-INHIBITORS OR ARB’S STILL NEEDED FOR CARDIOVASCULAR PREVENTION IN HIGH RISK PATIENTS? INSIGHTS FROM PROFESS AND TRANSCEND
- Telmisartan
- Newer Insights into the Biochemical Physiology of the Renin–Angiotensin System: Role of Angiotensin-(1-7), Angiotensin Converting Enzyme 2, and Angiotensin-(1-12)
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