The solution structure of the amino-terminal domain of human DNA polymerase ε subunit B is homologous to C-domains of AAA+ proteins
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Summary
A novel domain specific to the N-terminus of the B subunit of eukaryotic DNA polymerases ε is described, which represents the first C-domain fold not associated with an AAA+ protein.
- Type
- article
- Published
- 2008-08-02
- Cited by
- 31
- References
- 54
- Access
- Open access
- OpenAlex
- https://openalex.org/W2059045013
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:27521902
Keywords
Biology, B3 domain, DNA polymerase, Polymerase, DNA clamp
References
- AQUA and PROCHECK-NMR: Programs for checking the quality of protein structures solved by NMR
- Estimation of protein secondary structure from circular dichroism spectra: comparison of CONTIN, SELCON, and CDSSTR methods with an expanded reference set.
- Protein fold recognition using sequence profiles and its application in structural genomics.
- GeneDoc: Analysis and visualization of genetic variation
- Intraresidual HNCA: An experiment for correlating only intraresidual backbone resonances
- Origins of DNA replication in the three domains of life
- Completeness of NOEs in protein structure: a statistical analysis of NMR.
- Temporal order of evolution of DNA replication systems inferred by comparison of cellular and viral DNA polymerases
- Identification of homology in protein structure classification
- AAA+: A class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes.
- The CATH database: an extended protein family resource for structural and functional genomics
- On the origin of the histone fold
- Structural and functional similarities of prokaryotic and eukaryotic DNA polymerase sliding clamps.
- Compilation, alignment, and phylogenetic relationships of DNA polymerases.
- Two-dimensional NMR experiments for correlating carbon-13.beta. and proton.delta./.epsilon. chemical shifts of aromatic residues in 13C-labeled proteins via scalar couplings
- MOLMOL: a program for display and analysis of macromolecular structures.
- A gradient 13C NOESY-HSQC experiment for recording NOESY spectra of 13C-labeled proteins dissolved in H2O
- A novel family of DNA-polymerase-associated B subunits.
- Distinct roles of DNA polymerases delta and epsilon at the replication fork in Xenopus egg extracts
- Did DNA replication evolve twice independently?
Cited by
- Kinetic investigation of the polymerase and exonuclease activities of human DNA polymerase ε holoenzyme
- The Eukaryotic Replisome: a Guide to Protein Structure and Function
- On the Evolution of Proteins from Peptides
- DNA polymerase ε.
- Role of yeast DNA polymerase epsilon during DNA replication
- DNA replication and homologous recombination factors: acting together to maintain genome stability
- The eukaryotic replicative DNA polymerases take shape.
- Dpb2 integrates the leading-strand DNA polymerase into the eukaryotic replisome.
- Structural basis for processive DNA synthesis by yeast DNA polymerase ɛ
- Identification of a Ninein (NIN) mutation in a family with spondyloepimetaphyseal dysplasia with joint laxity (leptodactylic type)-like phenotype.
- Crystal Structure of the Human Pol α B Subunit in Complex with the C-terminal Domain of the Catalytic Subunit*
- Defective interaction between Pol2p and Dpb2p, subunits of DNA polymerase epsilon, contributes to a mutator phenotype in Saccharomyces cerevisiae
- Modulation of mutagenesis in eukaryotes by DNA replication fork dynamics and quality of nucleotide pools
- Domain Structures and Inter-Domain Interactions Defining the Holoenzyme Architecture of Archaeal D-Family DNA Polymerase
- Structure of a DNA Polymerase α-Primase Domain That Docks on the SV40 Helicase and Activates the Viral Primosome*
- Functional mapping of the fission yeast DNA polymerase δ B-subunit Cdc1 by site-directed and random pentapeptide insertion mutagenesis
- Solution structure of the N‐terminal domain of the archaeal D‐family DNA polymerase small subunit reveals evolutionary relationship to eukaryotic B‐family polymerases
- The C-terminus of Dpb2 is required for interaction with Pol2 and for cell viability
- Histones predate the split between bacteria and archaea
- Structure of the polymerase ε holoenzyme and atomic model of the leading strand replisome
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