Mechanisms of cigarette smoke-induced COPD: insights from animal models.
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Summary
Cigarette smoke-induced animal models of chronic obstructive pulmonary disease support the protease-antiprotease hypothesis of emphysema, although which cells and proteases are the crucial actors remains controversial.
- Type
- article
- Published
- 2008-04-01
- Cited by
- 301
- References
- 212
- OpenAlex
- https://openalex.org/W18223159
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:12251675
Keywords
Herd, Estrous cycle, Ice calving, Animal science, Biology
References
- Guinea pig pulmonary hypertension caused by cigarette smoke cannot be explained by capillary bed destruction.
- Inflammation of the airways and lung parenchyma in COPD: role of T cells.
- Cigarette smoke‐induced pulmonary inflammation, but not airway remodelling, is attenuated in chemokine receptor 5‐deficient mice
- Elastases and emphysema. Current assessment of the protease-antiprotease hypothesis.
- EXPERIMENTAL EMPHYSEMA: ITS PRODUCTION WITH PAPAIN IN NORMAL AND SILICOTIC RATS.
- Cigarette smoke-induced emphysema in guinea pigs is associated with diffusely decreased capillary density and capillary narrowing.
- Genetic risk factors for chronic obstructive pulmonary disease.
- Cor Pulmonale: An Overview
- Cigarette smoke causes rapid lipid peroxidation of rat tracheal epithelium.
- Respiratory-related neuronal activity in the nucleus ambiguus-retroambigualis complex and their responses to peripheral and central stimulation in the rat
- Inhibition of tobacco smoke-induced lung inflammation by a catalytic antioxidant.
- Tobacco smoke-induced lung emphysema in guinea pigs is associated with increased interstitial collagenase.
- IL-18 Is Induced and IL-18 Receptor α Plays a Critical Role in the Pathogenesis of Cigarette Smoke-Induced Pulmonary Emphysema and Inflammation1
- Black tea prevents cigarette smoke-induced apoptosis and lung damage
- Lipopolysaccharide challenge of humans as a model for chronic obstructive lung disease exacerbations.
- Lovastatin Enhances Clearance of Apoptotic Cells (Efferocytosis) with Implications for Chronic Obstructive Pulmonary Disease1
- Animal models of chronic obstructive pulmonary disease exacerbations.
- Cigarette smoke impairs elastin resynthesis in lungs of hamsters with elastase-induced emphysema.
- A Site on Laminin α5, AQARSAASKVKVSMKF, Induces Inflammatory Cell Production of Matrix Metalloproteinase-9 and Chemotaxis1
- Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease: GOLD Executive Summary Updated 2003
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- The role of animal models in the pharmacological evaluation of emerging anti-inflammatory agents for the treatment of COPD.
- Lymphoid follicles in (very) severe COPD: beneficial or harmful?
- In Utero Tobacco Smoke Exposure Alters Pulmonary Responses of Newborn Rats to Ozone
- Genetic ablation of the fpr1 gene confers protection from smoking-induced lung emphysema in mice.
- Role of RASEF hypermethylation in cigarette smoke-induced pulmonary arterial smooth muscle remodeling
- Phosphodiesterase inhibitors: history of pharmacology.
- ERK1/2 Promotes cigarette smoke-induced rat pulmonary artery smooth muscle cells proliferation and pulmonary vascular remodeling via up-regulating cycline1 expression
- Neuroimmune Interactions, Low-Dose Sarin Inhalation, and Gulf War Syndrome
- Cigarette Smoke-Induced Emphysema and Pulmonary Hypertension Can Be Prevented by Phosphodiesterase 4 and 5 Inhibition in Mice
- Airway Hydration and COPD
- Forsythiaside inhibits cigarette smoke-induced lung inflammation by activation of Nrf2 and inhibition of NF-κB.
- Resveratrol potentiates the effect of dexamethasone in rat model of acute lung inflammation.
- Smoking and High-Fat Diet: Risk Factors Regulating Emphysema Formation
- Acrolein effects in pulmonary cells: relevance to chronic obstructive pulmonary disease
- Cigarette Smoke Exposure as a Model of Inflammation Associated with COPD
- The role of soluble guanylyl cyclase in chronic obstructive pulmonary disease.
- Heme oxygenase-1-mediated autophagy protects against pulmonary endothelial cell death and development of emphysema in cadmium-treated mice.
- Caroli disease with bilateral severe bullous emphysema. An unknown component.
- Assessing particle and fiber toxicology in the respiratory system: the stereology toolbox
- Plasmid-based short hairpin RNA against cyclin D1 attenuated pulmonary vascular remodeling in smoking rats.
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