Glycated fetal calf serum affects the viability of an insulin-secreting cell line in vitro.
Explore this paper's citation graph
Summary
A pivotal role of the non-enzymatic glycation process in the onset and progression of diabetes during aging is suggested and a direct adverse effect of a glycated environment on the pancreatic islet cells is reported.
- Type
- article
- Published
- 2008-02-01
- Cited by
- 42
- References
- 49
- OpenAlex
- https://openalex.org/W2094871310
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:24480310
Keywords
Glycation, Oxidative stress, Viability assay, Insulin, Apoptosis
References
- Glycation-dependent, reactive oxygen species-mediated suppression of the insulin gene promoter activity in HIT cells.
- Type 2 diabetes: principles of pathogenesis and therapy
- Glycated high-density lipoprotein induces apoptosis of endothelial cells via a mitochondrial dysfunction.
- Enhanced cellular oxidant stress by the interaction of advanced glycation end products with their receptors/binding proteins.
- Dysregulation of insulin receptor substrate 2 in beta cells and brain causes obesity and diabetes.
- Glycoxidation and lipoxidation in atherogenesis.
- Role of resistin in diet-induced hepatic insulin resistance.
- Physical activity, obesity, and the incidence of type 2 diabetes in a high-risk population.
- Increased expression of cyclooxygenase-2 in human pancreatic islets treated with high glucose or ligands of the advanced glycation endproduct-specific receptor (AGER), and in islets from diabetic mice
- Advanced glycation end products induce apoptosis and procoagulant activity in cultured human umbilical vein endothelial cells.
- Oxidative Stress-mediated, Post-translational Loss of MafA Protein as a Contributing Mechanism to Loss of Insulin Gene Expression in Glucotoxic Beta Cells*
- Global prevalence of diabetes: estimates for the year 2000 and projections for 2030.
- Induction of apoptosis by glyoxal in human embryonic lung epithelial cell line L132.
- Prevention of glucose toxicity in HIT-T15 cells and Zucker diabetic fatty rats by antioxidants.
- Hyperglycemia causes oxidative stress in pancreatic beta-cells of GK rats, a model of type 2 diabetes.
- Lipid-induced beta-cell dysfunction in vivo in models of progressive beta-cell failure.
- Induction of glycation suppresses glucokinase gene expression in HIT-T15 cells
- Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1
- Free fatty acids in obesity and type 2 diabetes: defining their role in the development of insulin resistance and β‐cell dysfunction
- Chromatographic Quantitation of Plasma and Erythrocyte Pentosidine in Diabetic and Uremic Subjects
Cited by
- Biogerontology in Italy
- Effects of High Glucose Levels and Glycated Serum on GIP Responsiveness in the Pancreatic Beta Cell Line HIT-T15
- Vascular endothelial growth factor-C secretion is increased by advanced glycation end-products: possible implication in ocular neovascularization
- Advanced glycation end-products affect transcription factors regulating insulin gene expression.
- Pioglitazone attenuates the detrimental effects of advanced glycation end-products in the pancreatic beta cell line HIT-T15.
- Advanced Glycation End Products and Oxidative Stress in Type 2 Diabetes Mellitus
- Kinetics of Glycoxidation of Bovine Serum Albumin by Glucose, Fructose and Ribose and Its Prevention by Food Components
- D-Ribose Induces Cellular Protein Glycation and Impairs Mouse Spatial Cognition
- D-ribose in glycation and protein aggregation.
- Retinal Pigment Epithelial Cells Express a Functional Receptor for Glucagon-Like Peptide-1 (GLP-1)
- Glucagon-like peptide-1 counteracts the detrimental effects of Advanced Glycation End-Products in the pancreatic beta cell line HIT-T 15.
- An Emerging Role of Glucagon-Like Peptide-1 in Preventing Advanced-Glycation-End-Product-Mediated Damages in Diabetes
- Glucagon-Like Peptide-1 Secreting Cell Function as well as Production of Inflammatory Reactive Oxygen Species Is Differently Regulated by Glycated Serum and High Levels of Glucose
- Rapid glycation with D-ribose induces globular amyloid-like aggregations of BSA with high cytotoxicity to SH-SY5Y cells
- Inhibition of the receptor for advanced glycation endproducts (RAGE) protects pancreatic β-cells.
- Ribosylation of bovine serum albumin induces ROS accumulation and cell death in cancer line (MCF-7)
- Stimulatory Role of Glycated Fetal Bovine Serum Along with Iron on In Vitro Production of Insulin by Differentiated Mouse Embryonic Stem Cells
- Glucagon-Like Peptide-1 Triggers Protective Pathways in Pancreatic Beta-Cells Exposed to Glycated Serum
- Advanced glycation end products as environmental risk factors for the development of type 1 diabetes.
- Effects of fructosamine-3-kinase deficiency on function and survival of mouse pancreatic islets after prolonged culture in high glucose or ribose concentrations.
Related papers
- ADVANCED GLYCATION END PRODUCTS AND THIOBARBITURIC ACID REACTIVE SUBSTANCE IN GINGIVAL TISSUES OF DIABETIC AND NON-DIABETIC PATIENTS WITH CHRONIC PERIODONTITIS
- Chicken albumin exhibits natural resistance to glycation Part B Biochemistry & molecular biology
- Inhibition of lens crystallin glycation and high molecular weight aggregate formation by aspirin in vitro and in vivo.
- Differential glycation of rat alpha-, beta- and gamma-crystallins.
- Chicken albumin exhibits natural resistance to glycation.
- Glycation of the human erythrocyte glucose transporter in vitro and its functional consequences.
- Fewer Exposed Lysine Residues May Explain Relative Resistance of Chicken Serum Albumin to In Vitro Protein Glycation in Comparison to Bovine Serum Albumin
- In vitro glycation of human immunoglobulin G.
- In vitro human serum albumin glycation monitored by Terahertz spectroscopy
- In vitro glycation of human immunoglobulin G