Effects of atorvastatin and simvastatin on atrial plateau currents.
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Summary
The results suggest that atorvastatin and SVA alter Kv1.5 and Kv4.3 channel activity following a complex mechanism that does not imply the binding of the drug to the channel pore, and shortened, the duration of mouse atrial action potentials.
- Type
- article
- Published
- 2007-05-01
- Cited by
- 53
- References
- 52
- OpenAlex
- https://openalex.org/W17466325
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:5920127
Keywords
Passiflora, Geography, Botany, Biology
References
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Cited by
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- Usefulness of targeting lymphocyte Kv1.3-channels in the treatment of respiratory diseases
- Effects of MiRP1 and DPP6 β‐subunits on the blockade induced by flecainide of KV4.3/KChIP2 channels
- Regulación de los canales Kir 2.1 y de la corriente cardíaca humana IK 1 por el óxido nítrico
- HMG-CoA reductase inhibitors pravastatin, lovastatin and simvastatin suppress delayed rectifier K^+-channel currents in murine thymocytes
- Cholesterol and cardiac arrhythmias
- Red cardiovascular HERACLES
- Antiarrhythmic Effects of Simvastatin in Canine Pulmonary Vein Sleeve Preparations
- Update on the Association of Inflammation and Atrial Fibrillation
- Protective role of simvastatin on isolated rabbit atrioventricular node during experimental atrial fibrillation model: role in rate control of ventricular beats
- Different Subcellular Populations of L-type Ca2+ Channels Exhibit Unique Regulation and Functional Roles in Cardiomyocytes
- Endocannabinoids and cannabinoid analogues block human cardiac Kv4.3 channels in a receptor-independent manner.
- Simvastatin attenuates sympathetic hyperinnervation to prevent atrial fibrillation during the postmyocardial infarction remodeling process.
- Simvastatin inhibits acidic extracellular pH-activated, outward rectifying chloride currents in RAW264.7 monocytic-macrophage and human peripheral monocytes.
- Inflammation and Atrial Fibrillation
- Synchrotron X-ray powder diffraction data of atorvastatin
- Inhibition of the mevalonate pathway ameliorates anoxia-induced down-regulation of FKBP12.6 and intracellular calcium handling dysfunction in H9c2 cells.
- Fluvastatin Reduces Pulmonary Vein Spontaneous Activity Through Nitric Oxide Pathway
- [The HERACLES Cardiovascular Network].
- Exploring Leishmania donovani 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) as a potential drug target by biochemical, biophysical and inhibition studies.
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