Monocytosis is an adverse prognostic factor for survival in younger patients with primary myelofibrosis.
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Summary
The current study reveals that an absolute monocyte count of > or =1 x 10(9)L(-1) carries an independent predictive value for an inferior survival, in addition to that provided by hemoglobin level, platelet count, and leukocyte count.
- Type
- article
- Published
- 2007-11-01
- Cited by
- 99
- References
- 25
- OpenAlex
- https://openalex.org/W17397921
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:13508583
Keywords
Mathematics, Field (mathematics), Calculus (dental), Geography, Pure mathematics
References
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- Allogeneic stem cell transplantation for agnogenic myeloid metaplasia: a European Group for Blood and Marrow Transplantation, Société Française de Greffe de Moelle, Gruppo Italiano per il Trapianto del Midollo Osseo, and Fred Hutchinson Cancer Research Center Collaborative Study.
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Cited by
- JAK2 inhibitor therapy in myeloproliferative disorders: rationale, preclinical studies and ongoing clinical trials
- CMML: Clinical and molecular aspects
- Determinantes celulares, plasmáticos y genéticos de riesgo de trombosis y hemorragia en pacientes con neoplasias mieloproliferativas crónicas filadelfia negativo
- Absolute monocytosis at diagnosis correlates with survival in diffuse large B‐cell lymphoma—possible link with monocytic myeloid‐derived suppressor cells
- Synergism between fibronectin and transforming growth factor-β1 in the production of substance P in monocytes of patients with myelofibrosis
- Risk factors for leukemic transformation in patients with primary myelofibrosis
- An Immune Dysregulation in MPN
- Chronic Myelomonocytic Leukemia Prognostic Classification and Management: Evidence Base and Current Practice
- Reduced-Intensity Conditioning Followed by Allogeneic Hematopoietic Stem Cell Transplantation in Myelofibrosis
- Identification of patients with poorer survival in primary myelofibrosis based on the burden of JAK2V617F mutated allele.
- Choosing between stem cell therapy and drugs in myelofibrosis
- Does monocyte count have prognostic significance in cancer?
- Phase 2 study of CEP-701, an orally available JAK2 inhibitor, in patients with primary or post-polycythemia vera/essential thrombocythemia myelofibrosis.
- Progression of myeloproliferative neoplasms to myelofibrosis and acute leukaemia
- Essential thrombocythemia, polycythemia vera, and myelofibrosis: Current management and the prospect of targeted therapy
- JAK2 inhibitors: A reality? A hope?
- Age and platelet count are IPSS‐independent prognostic factors in young patients with primary myelofibrosis and complement IPSS in predicting very long or very short survival
- Chronic kidney disease in patients with the Philadelphia-negative chronic myeloproliferative neoplasms.
- Monocyte IL-2Ralpha expression is associated with thrombosis and the JAK2V617F mutation in myeloproliferative neoplasms.
- Conventional and New Treatment Modalities in Myelofibrosis and the Current Role of Transplantation
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