Receptor tyrosine kinases positively regulate BACE activity and Amyloid-β production through enhancing BACE internalization

Keywords

Small nucleolar RNA, Biology, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Ribosomal RNA

References

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• Regulation of Alzheimer’s disease-relevant protein processing in human neurons of the LUHMES cell lineD. Scholz — 2011
• Alzheimer's Disease-Related Loss of Pin1 Function Influences the Intracellular Localization and the Processing of AβPPLucia Pastorino, Suk Ling, Martin Balaštík — 2012
• Increased AICD generation does not result in increased nuclear translocation or activation of target gene transcription.Elaine Waldron, Simone Isbert, Andreas Kern — 2008
• Cholesterol-depletion corrects APP and BACE1 misstrafficking in NPC1-deficient cells.Martina Malnar, Marko Košiček, Ana Lisica — 2012
• Reduced amyloid deposition in mice overexpressing RTN3 is adversely affected by preformed dystrophic neuritesQi Shi, Marguerite Prior, Wanxia He — 2009
• Activation of Amyloid Precursor Protein Processing by Growth Factors is Dependent on Ras GTPase ActivityLoredana Amigoni, Michela Ceriani, Fiorella Belotti — 2011
• Alteration of β-secretase traffic by the receptor tyrosine kinase signaling pathway – a new mechanism for regulating Alzheimer's β-amyloid productionYun‐wu Zhang, Huaxi Xu — 2007
• Control of Aβ release from human neurons by differentiation status and RET signaling.Diana Scholz, Yana Chernyshova, Marcel Leist — 2013
• Decreased expression of GGA3 protein in Alzheimer's disease frontal cortex and increased co-distribution of BACE with the amyloid precursor protein.Claudia Santosa, Stefanie Rasche, Adel Barakat — 2011
• Relevance of Amyloid Precursor-like Protein 2 C-terminal Fragments in Pancreatic Cancer CellsHaley L. Peters, Amit Tuli, Xiaojian Wang — 2012
• Central Angiotensin II Stimulation Promotes β Amyloid Production in Sprague Dawley RatsDonglin Zhu, Jingping Shi, Yingdong Zhang — 2011
• The novel protein MANI modulates neurogenesis and neurite-cone growthManisha Mishra, Hiroyasu Akatsu, Klaus Heese — 2011
• Optimisation of BACE1 inhibition of tripartite structures by modification of membrane anchors, spacers and pharmacophores - development of potential agents for the treatment of Alzheimer's disease.Philipp Linning, Ute Haußmann, Isaak Beyer — 2012
• Advances with RNA interference in Alzheimer’s disease researchWeien Yuan, Shun Chen, Xuemei Ge — 2013
• Novel disease-modifying therapeutics for the treatment of Alzheimer’s diseaseGabriel C. Léger, Fadi Massoud — 2013
• Mild Oxidative Stress Induces Redistribution of BACE1 in Non-Apoptotic Conditions and Promotes the Amyloidogenic Processing of Alzheimer’s Disease Amyloid Precursor ProteinJiang‐Li Tan, Qiao‐Xin Li, Giuseppe D. Ciccotosto — 2013
• Common themes in PrP signaling: the Src remains the sameKatharina Ochs, Edward Málaga-Trillo — 2014
• Nuclear signaling by the APP intracellular domain occurs predominantly through the amyloidogenic processing pathwayZoë V. Goodger, Lawrence Rajendran, Annette Trutzel — 2009
• N-terminal Domains Elicit Formation of Functional Pmel17 Amyloid Fibrils*Brenda Watt, Guillaume van Niel, Douglas M. Fowler — 2009

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