Dysregulation of Src Family Kinases in Mast Cells from Epilepsy-Resistant ASK versus Epilepsy-Prone EL Mice1
Explore this paper's citation graph
Summary
It is suggested that reduced activity of Lyn, a negative regulator of mast cell activation, underlies the susceptibility of ASK mice to anaphylaxis and implies that dysregulation of Lyn and other Src family kinases contributes to epileptogenesis.
- Type
- article
- Published
- 2007-01-01
- Cited by
- 27
- References
- 64
- Access
- Open access
- OpenAlex
- https://openalex.org/W17182584
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:17149135
Keywords
Schrödinger's cat, State (computer science), Mode (computer interface), Mathematical physics, Physics
References
- Subtype‐specific regulation of recombinant NMDA receptor‐channels by protein tyrosine kinases of the src family.
- Kindling enhances sensitivity of CA3 hippocampal pyramidal cells to NMDA
- Redundant and Opposing Functions of Two Tyrosine Kinases, Btk and Lyn, in Mast Cell Activation1
- Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases
- Monoclonal dinitrophenyl-specific murine IgE antibody: preparation, isolation, and characterization.
- Impaired tyrosine phosphorylation and Ca2+ mobilization, but not degranulation, in lyn-deficient bone marrow-derived mast cells.
- Genetic evidence for Lyn as a negative regulator of IL-4 signaling.
- Higher seizure susceptibility and enhanced tyrosine phosphorylation of N-methyl-D-aspartate receptor subunit 2B in fyn transgenic mice.
- Cutting Edge: Transmembrane Phosphoprotein Csk-Binding Protein/Phosphoprotein Associated With Glycosphingolipid-Enriched Microdomains as a Negative Feedback Regulator of Mast Cell Signaling Through the FcεRI
- Enhanced susceptibility of audiogenic seizures in Fyn-kinase deficient mice.
- Transmembrane adaptor proteins: organizers of immunoreceptor signalling
- Engagement of the high-affinity IgE receptor activates src protein-related tyrosine kinases
- Mast cells as sentinels of innate immunity.
- Transphosphorylation of Bruton’s Tyrosine Kinase on Tyrosine 551 Is Critical for B Cell Antigen Receptor Function*
- Regulation of mast-cell and basophil function and survival by IgE
- Biochemical evidence for enhanced sensitivity to N-methyl-D-aspartate in the hippocampal formation of kindled rats.
- Three-dimensional structure of the tyrosine kinase c-Src
- Epileptiform discharges in the human dysplastic neocortex: In vitro physiology and pharmacology
- Effects of tea infusions of various varieties or different manufacturing types on inhibition of mouse mast cell activation.
- Src, N-methyl-D-aspartate (NMDA) receptors, and synaptic plasticity.
Cited by
- The genetic basis for response to the Ketogenic diet in drug-resistant epilepsy
- SH2 Domain-Containing Phosphatase-2 Protein-Tyrosine Phosphatase Promotes FcεRI-Induced Activation of Fyn and Erk Pathways Leading to TNFα Release from Bone Marrow-Derived Mast Cells1
- PAG - a multipurpose transmembrane adaptor protein
- Oncogenic association of the Cbp/PAG adaptor protein with the Lyn tyrosine kinase in human B-NHL rafts.
- Regulation of FynT Function by Dual Domain Docking on PAG/Cbp*
- Adapters in the organization of mast cell signaling
- Transmembrane Adaptor Proteins in the High-Affinity IgE Receptor Signaling
- Understanding the mechanisms of anaphylaxis
- Channel catfish leukocyte immune-type receptor mediated inhibition of cellular cytotoxicity is facilitated by SHP-1-dependent and -independent mechanisms.
- Gliomas and seizures
- New insights on mast cell activation via the high affinity receptor for IgE.
- 2-Hydroxypropyl-β-Cyclodextrin Acts as a Novel Anticancer Agent
- Transmembrane Adaptor Protein PAG/CBP Is Involved in both Positive and Negative Regulation of Mast Cell Signaling
- Loss of TRPC1‐mediated Ca2+ influx contributes to impaired degranulation in Fyn‐deficient mouse bone marrow‐derived mast cells
- Basophils and IgE: Linking the Allergic Environment to Autoimmunity
- Inducing an anergic state in mast cells and basophils without secretion.
- DEFINING THE ROLE OF THE SHP2 PROTEIN TYROSINE PHOSPHATASE IN FcepsilonRI SIGNALING IN MAST CELLS
- Differential Lyn-dependence of the SHIP1-deficient mast cell phenotype
- Immunoregulatory effect of mast cells influenced by microbes in neurodegenerative diseases.
- Role of the Fyn-PKCδ Signaling in SE-induced Neuroinflammation and Epileptogenesis in Experimental Models of Temporal Lobe Epilepsy
Related papers
- Conditional generation of Fock states and Schrödinger-cat states via adding multiple photons to a squeezed vacuum state
- Properties of superposition of squeezed states
- The quantum sling and the Schrödinger cat
- Quantum Properties of Three-Mode Squeezed Number State
- SU(1, 1) squeezed state
- Squeezing in multimode Schrödinger cat states