Pax2/5/8 proteins promote cell survival in C. elegans

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Summary

Using genetic and molecular experiments, this work shows that the Pax proteins act as transcriptional regulators of ced-9, the C. elegans bcl-2 gene, and underscores the importance of transcriptional regulation of core apoptotic pathway genes in influencing cell survival.

Type
article
Published
2006-11-01
Cited by
57
References
54

Keywords

Biology, Programmed cell death, Somatic cell, Cell biology, Transcription factor

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