Redox Regulation of Human Thioredoxin Network
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Summary
This review focuses on TRX and its related molecules, and discusses the role of TRX-dependent redox regulation in oxidative stress-induced signal transduction.
- Type
- review
- Published
- 2006-09-01
- Cited by
- 164
- References
- 97
- OpenAlex
- https://openalex.org/W1967707355
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:23259124
Keywords
Thioredoxin, Oxidative stress, Cell biology, Reactive oxygen species, Signal transduction
References
- Distinct effects of thioredoxin and antioxidants on the activation of transcription factors NF-kappa B and AP-1.
- AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1.
- Hypoxia-ischemia induces thioredoxin expression and nitrotyrosine formation in new-born rat brain
- Impaired fatty acid utilization in thioredoxin binding protein‐2 (TBP‐2)‐deficient mice: a unique animal model of Reye syndrome
- Nuclear factor kappaB transactivation is increased but is not involved in the proliferative effects of thioredoxin overexpression in MCF-7 breast cancer cells.
- Oxidoreductive regulation of nuclear factor kappa B. Involvement of a cellular reducing catalyst thioredoxin.
- Vitamin D3 Up-Regulated Protein 1 Mediates Oxidative Stress Via Suppressing the Thioredoxin Function1
- Human eosinophil cytotoxicity-enhancing factor. Eosinophil-stimulating and dithiol reductase activities of biosynthetic (recombinant) species with COOH-terminal deletions.
- H2O2 and antioxidants have opposite effects on activation of NF‐kappa B and AP‐1 in intact cells: AP‐1 as secondary antioxidant‐responsive factor.
- The Cytokine Macrophage Migration Inhibitory Factor Reduces Pro-Oxidative Stress-Induced Apoptosis1
- Mice Lacking Thioredoxin-interacting Protein Provide Evidence Linking Cellular Redox State to Appropriate Response to Nutritional Signals*
- Loss of Thioredoxin-Binding Protein-2/Vitamin D3 Up-Regulated Protein 1 in Human T-Cell Leukemia Virus Type I-Dependent T-Cell Transformation
- Mammalian thioredoxin is a direct inhibitor of apoptosis signal‐regulating kinase (ASK) 1
- TMX, a human transmembrane oxidoreductase of the thioredoxin family: the possible role in disulfide-linked protein folding in the endoplasmic reticulum.
- Thioredoxin regulates the DNA binding activity of NF-kappa B by reduction of a disulphide bond involving cysteine 62.
- Glutaredoxin Exerts an Antiapoptotic Effect by Regulating the Redox State of Akt*
- Thioredoxin-1 Ameliorates Myosin-Induced Autoimmune Myocarditis by Suppressing Chemokine Expressions and Leukocyte Chemotaxis in Mice
- The redox/DNA repair protein, Ref-1, is essential for early embryonic development in mice.
- Circulating thioredoxin suppresses lipopolysaccharide-induced neutrophil chemotaxis
- Regulation of Macrophage Migration Inhibitory Factor and Thiol-specific Antioxidant Protein PAG by Direct Interaction*
Cited by
- Mitochondrial Regulation of Cell Cycle and Proliferation
- Subcytotoxic mercury chloride inhibits gap junction intercellular communication by a redox- and phosphorylation-mediated mechanism.
- Gambogic acid deactivates cytosolic and mitochondrial thioredoxins by covalent binding to the functional domain.
- Thioredoxin and redox signaling: Roles of the thioredoxin system in control of cell fate.
- Multifunctional Thioredoxin-Like Protein from the Gastrointestinal Parasitic Nematodes Strongyloides ratti and Trichuris suis Affects Mucosal Homeostasis
- Mecanismos de proliferación dependientes del estado redox celular: rol de AKT y otras kinasas involucradas en la progresión del ciclo celular
- Unveiling the roles of the glutathione redox system in vivo by analyzing genetically modified mice
- Thioredoxin Superfamily and Its Effects on Cardiac Physiology and Pathology
- A mammalian monothiol glutaredoxin, Grx3, is critical for cell cycle progression during embryogenesis
- Methods for studying redox cycling of thioredoxin in mediating preconditioning-induced survival genes and proteins.
- Loss of mitochondrial thioredoxin reductase delays angiogenic switch and impairs tumour growth
- Diagnostic and prognostic value of serum thioredoxin and DJ-1 in non-small cell lung carcinoma patients
- CP-154,526 Modifies CREB Phosphorylation and Thioredoxin-1 Expression in the Dentate Gyrus following Morphine-Induced Conditioned Place Preference
- Resveratrol: Its Biologic Targets and Functional Activity
- 6-Dehydrogingerdione, an active constituent of dietary ginger, induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human breast cancer cells.
- Thioredoxin-1 expression regulated by morphine in SH-SY5Y cells.
- Targeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide
- Activation of translation via reduction by thioredoxin–thioredoxin reductase in Saccharomyces cerevisiae
- Comparative study of two thioredoxins from common cutworm (Spodoptera litura): cloning, expression, and functional characterization.
- Icariin Synergizes with Arsenic Trioxide to Suppress Human Hepatocellular Carcinoma
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