An evaluation of molecular markers for improved detection of breast cancer metastases in sentinel nodes
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Summary
As IHC analysis resulted in a 77% detection rate compared with 37% for haematoxylin and eosin analysis, it is considered that IHC is essential in order not to miss SN micrometastases.
- Type
- article
- Published
- 2006-02-27
- Cited by
- 36
- References
- 87
- Access
- Open access
- OpenAlex
- https://openalex.org/W16505281
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:21990434
Keywords
Jackknife resampling, Outlier, Mathematics, Estimator, Exponential distribution
References
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Cited by
- Technical limits of comparison of step-sectioning,immunohistochemistry and RT-PCR on breast cancer sentinel nodes: a study on methacarn-fixed tissue
- Tipos especiais histológicos de carcinomas da mama : perfil imunoistoquímico com ênfase na classificação molecular
- Mammaglobin 1: not only a breast‐specific and tumour‐specific marker, but also a hormone‐responsive endometrial protein
- Pathology Issues Related to SN Procedures and Increased Detection of Micrometastases and Isolated Tumor Cells
- Management strategy of early-stage breast cancer patients with a positive sentinel lymph node: With or without axillary lymph node dissection.
- Molecular markers of breast axillary lymph node metastasis
- Prostate-derived Ets transcription factor overexpression is associated with nodal metastasis and hormone receptor positivity in invasive breast cancer.
- Patterns of DNA copy number changes in sentinel lymph node breast cancer metastases
- An improved axillary staging system using the OSNA assay does not modify the therapeutic management of breast cancer patients
- Lymphangiogenesis and Lymphatic Metastasis in Breast Cancer
- The changing face of percutaneous image-guided biopsy: molecular profiling and genomic analysis in current practice.
- Modern Trends in Imaging X: Spectral Imaging in Preclinical Research and Clinical Pathology
- Molecular diagnostics in the cytology laboratory: slowly making its way there
- Molecular detection of breast cancer metastasis in sentinel lymph nodes by reverse transcriptase polymerase chain reaction (RT-PCR): identifying, evaluating and establishing multi-marker panels
- The clinical significance of disseminated tumor cells in breast cancer
- A small subgroup of operable breast cancer patients with poor prognosis identified by quantitative real-time RT-PCR detection of mammaglobin A and trefoil factor 1 mRNA expression in bone marrow
- Molecular assessment of sentinel lymph node in breast cancer management
- Breast cancer sentinel lymph node and axillary lymphadenectomy: new tools for new challenges
- Intra-operative rapid diagnostic method based on CK19 mRNA expression for the detection of lymph node metastases in breast cancer
- Validity of frozen section in sentinel lymph node biopsy for the staging in oral and oropharyngeal squamous cell carcinoma
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