Gene3D: modelling protein structure, function and evolution
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Summary
The Gene3D release 4 database and web portal provide a combined structural, functional and evolutionary view of the protein world, focussed on providing structural annotation for protein sequences without structural representatives.
- Type
- article
- Published
- 2005-12-28
- Cited by
- 67
- References
- 25
- Access
- Open access
- OpenAlex
- https://openalex.org/W16381865
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:9651429
Keywords
Chemistry
References
- MUSCLE: a multiple sequence alignment method with reduced time and space complexity
- Gene Ontology Consortium: The Gene Ontology (GO) database and informatics resource
- Identification and distribution of protein families in 120 completed genomes using Gene3D
- Evolution of protein superfamilies and bacterial genome size.
- Assessing strategies for improved superfamily recognition
- BioMap: gene family based integration of heterogeneous biological databases using AutoMed metadata
- Basic Charge Clusters and Predictions of Membrane Protein Topology
- MINT: the Molecular INTeraction database
- The CATH Domain Structure Database and related resources Gene3D and DHS provide comprehensive domain family information for genome analysis
- Integr8 and Genome Reviews: integrated views of complete genomes and proteomes
- An efficient algorithm for large-scale detection of protein families.
- SCOP database in 2004: refinements integrate structure and sequence family data
- Multi-domain proteins in the three kingdoms of life: orphan domains and other unassigned regions.
- SMART 4.0: towards genomic data integration
- The KEGG resource for deciphering the genome
- CluSTr: a database of clusters of SWISS-PROT+TrEMBL proteins
- The SUPERFAMILY database in 2004: additions and improvements
- The Biomolecular Interaction Network Database and related tools 2005 update
- The COG database: an updated version includes eukaryotes
- The Distributed Annotation System
Cited by
- Protein domain prediction.
- Large-Scale Evolutionary Analysis of Genes and Supergene Clusters from Terpenoid Modular Pathways Provides Insights into Metabolic Diversification in Flowering Plants
- A pattern mining approach toward discovering generalized sequence signatures
- Automated structural annotation of the malaria proteome and identification of candidate proteins for modelling and crystallization studies
- Étude des mécanismes impliqués dans la tolérance à l'allogreffe cardiaque chez le rat
- Prediction and integration of regulatory and protein-protein interactions.
- Target selection for structural genomics: an overview.
- Index-based algorithms for motif search and their integration in a system for differential genome analysis
- Viral Proteins Acquired from a Host Converge to Simplified Domain Architectures
- Local Function Conservation in Sequence and Structure Space
- Towards fully automated structure-based function prediction in structural genomics: a case study.
- Annotating the human proteome: beyond establishing a parts list.
- Domain-based and family-specific sequence identity thresholds increase the levels of reliable protein function transfer.
- LIMLE, a New Molecule Over-Expressed following Activation, Is Involved in the Stimulatory Properties of Dendritic Cells
- The CATH database
- Predicting Protein Function with Hierarchical Phylogenetic Profiles: The Gene3D Phylo-Tuner Method Applied to Eukaryotic Genomes
- Sequence Similarity Network Reveals Common Ancestry of Multidomain Proteins
- In Silico Characterization of Proteins: UniProt, InterPro and Integr8
- Data Pushing: A Fly-Centric Guide to Bioinformatics Tools
- Domain Architecture Comparison for Multidomain Homology Identification
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