Reliable prediction of transcription factor binding sites by phylogenetic verification.

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Summary

A statistical methodology that largely improves the accuracy in computational predictions of transcription factor (TF) binding sites in eukaryote genomes and is coupled with any motif-finding algorithm that searches for overrepresented sequence motifs in individual species and can increase the accuracy of the coupled motif- finding algorithm.

Type
article
Published
2005-11-22
Cited by
46
References
42

Keywords

Nitromethane, Ab initio, Materials science, Computational chemistry, Chemistry

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