Extracellular release of BACE1 holoproteins from human neuronal cells.

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Summary

During the characterization of BACE1 shedding from human neuroblastoma SH-SY5Y cells stably expressing BACE 1, it was unexpectedly found that detectable amounts of Bace1 holoproteins were released extracellularly along with soluble BACE2, suggesting that the release of B ACE1 holiproteins may be a physiologically relevant cellular process.

Type
dissertation
Published
2005-12-16
Cited by
28
References
41

Keywords

Humanities, Physics, Political science, Art

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