Testosterone in older men after the Institute of Medicine Report: where do we go from here?
Explore this paper's citation graph
Summary
The US National Academies Institute of Medicine's recent report recommends that the National Institutes of Health support small efficacy trials aimed at treatment of androgen deficiency-related clinical conditions, but not a large, randomized trial to elucidate risk-benefit ratios, likely to delay, rather than foster, progress.
- Type
- article
- Published
- 2005-06-01
- Cited by
- 47
- References
- 105
- OpenAlex
- https://openalex.org/W16096168
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:46719204
Keywords
Computer science, Political science
References
- Effects of transdermal testosterone on bone and muscle in older men with low bioavailable testosterone levels.
- A novel testosterone gel formulation normalizes androgen levels in hypogonadal men, with improvements in body composition and sexual function
- Androgen treatment of middle-aged, obese men: effects on metabolism, muscle and adipose tissues.
- The effects of testosterone treatment on body composition and metabolism in middle-aged obese men.
- Cognitive changes associated with supplementation of testosterone or dihydrotestosterone in mildly hypogonadal men: a preliminary report.
- Age-related changes in whole-body amino acid kinetics and protein turnover in rats.
- Sarcopenia and hormonal changes
- Increase in bone density and lean body mass during testosterone administration in men with acquired hypogonadism.
- Increased incidence of diagnosed depressive illness in hypogonadal older men.
- Testosterone replacement in older hypogonadal men: a 12-month randomized controlled trial.
- Sexual behavior in healthy married elderly men
- Longitudinal evaluation of serum androgen levels in men with and without prostate cancer
- Free testosterone and risk for Alzheimer disease in older men
- Reproductive hormones in aging men. I. Measurement of sex steroids, basal luteinizing hormone, and Leydig cell response to human chorionic gonadotropin.
- Association of bioavailable, free, and total testosterone with insulin resistance: influence of sex hormone-binding globulin and body fat.
- Contribution of body fatness and adipose tissue distribution to the age variation in plasma steroid hormone concentrations in men: the HERITAGE Family Study.
- Prevalence of cognitive impairment
- Long-term testosterone gel (AndroGel) treatment maintains beneficial effects on sexual function and mood, lean and fat mass, and bone mineral density in hypogonadal men.
- Risk factors for osteoporotic fractures in elderly men.
- Increased premature mortality of competitive powerlifters suspected to have used anabolic agents.
Cited by
- Gender‐based cardiometabolic risk evaluation in minority and non‐minority men grading the evidence of non‐traditional determinants of cardiovascular risk
- The Natural History of Symptomatic Androgen Deficiency in Men: Onset, Progression, and Spontaneous Remission
- Hypogonadism among Jordanian men with type 2 diabetes: Prevalence and associated factor
- It's time for a large, long-term study of testosterone supplementation in hypogonadal older men: a primary care view
- Cardiovascular aspects of sexual medicine.
- Treatment of symptomatic androgen deficiency: results from the Boston Area Community Health Survey.
- Prevalence of low testosterone levels in men with type 2 diabetes mellitus: a cross-sectional study
- Aging effects on oxidative phosphorylation in rat adrenocortical mitochondria.
- A Slight Variation in the Age of Rats Commonly used as a Carotid Artery Injury Model Results in a Large Difference in Neointima Formation
- The relative contributions of aging, health, and lifestyle factors to serum testosterone decline in men.
- Testosterone supplementation and the prostate: a review of the safety issue
- Evidence that age‐related changes in p38 MAP kinase contribute to the decreased steroid production by the adrenocortical cells from old rats
- Androgen Administration to Aged Male Mice Increases Anti-Anxiety Behavior and Enhances Cognitive Performance
- Testosterone Replacement Therapy in Hypogonadal Men: Assessing Benefits, Risks, and Best Practices
- Testosterone level and the effect of levodopa and agonists in early Parkinson disease: results from the INSPECT cohort
- A Telfairia Occidentalis Seed-incorporated Diet May Be Useful in Inhibiting the Induction of Experimental Andropause
- Influence of sex steroid hormones on cerebrovascular function.
- Population-based patterns of prescription androgen use, 1976-2008
- Hormones in wellness and disease prevention: common practices, current state of the evidence, and questions for the future.
- An investigation into the relationship between age and physiological function in highly active older adults
Related papers
No related papers recorded.