Acetylcholine Receptors Direct Rapsyn Clusters to the Neuromuscular Synapse in Zebrafish
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Summary
The ability of rapsyn clusters to localize effectively to subsynaptic sites also was rescued in large part and points to direct involvement of the AChR molecule in restricting receptor-rapsy clusters to the synapse.
- Type
- article
- Published
- 2004-06-16
- Cited by
- 54
- References
- 37
- Access
- Open access
- OpenAlex
- https://openalex.org/W15201319
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:522133
Keywords
Flash (photography), Computer graphics (images), Computer science, Art, Visual arts
References
- Long-Term Desensitization of Nicotinic Acetylcholine Receptors Is Regulated via Protein Kinase A-Mediated Phosphorylation
- The Myristoylated Protein Rapsyn is Cotargeted with the Nicotinic Acetylcholine Receptor to the Postsynaptic Membrane via the Exocytic Pathway
- Induction, assembly, maturation and maintenance of a postsynaptic apparatus
- Rapsyn Escorts the Nicotinic Acetylcholine Receptor Along the Exocytic Pathway via Association with Lipid Rafts
- Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors
- Optical Measurements of Presynaptic Release in Mutant Zebrafish Lacking Postsynaptic Receptors
- An altered intron inhibits synthesis of the acetylcholine receptor alpha-subunit in the paralyzed zebrafish mutant nic1.
- Paralytic Zebrafish Lacking Acetylcholine Receptors Fail to Localize Rapsyn Clusters to the Synapse
- Genes controlling and mediating locomotion behavior of the zebrafish embryo and larva.
- Acetylcholine receptor epsilon-subunit deletion causes muscle weakness and atrophy in juvenile and adult mice.
- End-plate acetylcholine receptor deficiency due to nonsense mutations in the epsilon subunit.
- ACh receptor-rich membrane domains organized in fibroblasts by recombinant 43-kildalton protein
- The nicotinic acetylcholine receptor gene family of the pufferfish, Fugu rubripes.
- Acetylcholinesterase is required for neuronal and muscular development in the zebrafish embryo
- Congenital myasthenic syndrome caused by novel loss-of-function mutations in the human AChR epsilon subunit gene.
- Increased neuromuscular activity causes axonal defects and muscular degeneration
- Identification of a transmembrane glycoprotein specific for secretory vesicles of neural and endocrine cells
- The postsynaptic 43K protein clusters muscle nicotinic acetylcholine receptors in Xenopus oocytes.
- Rapsyn is required for MuSK signaling and recruits synaptic components to a MuSK-containing scaffold.
- Multiple conductance classes of mouse nicotinic acetylcholine receptors expressed in Xenopus oocytes.
Cited by
- Synapse Formation and Neuromuscular Transmission in a Zebrafish Choline Acetyltransferase Mutant
- Increased ratio of rapsyn to ACh receptor stabilizes postsynaptic receptors at the mouse neuromuscular synapse
- The molecular determinants of synaptic current kinetics at zebrafish neuromuscular junctions
- Regulation of Nicotinic Acetylcholine Receptor Stability at the Mouse Neuromuscular Junction.
- Zebrafish mutants of the neuromuscular junction: swimming in the gene pool
- A Single Mutation in the Acetylcholine Receptor δ-Subunit Causes Distinct Effects in Two Types of Neuromuscular Synapses
- Muscular contractions in the zebrafish embryo are necessary to reveal thiuram-induced notochord distortions.
- Development of Skeletal Muscle Sodium and Potassium Currents in Zebrafish sofa potato Mutants
- The Knockdown of αkap Alters the Postsynaptic Apparatus of Neuromuscular Junctions in Living Mice
- Overexpression of rapsyn in rat muscle increases acetylcholine receptor levels in chronic experimental autoimmune myasthenia gravis.
- Secondary motoneurons in juvenile and adult zebrafish: Axonal pathfinding errors caused by embryonic nicotine exposure
- A mutation in serca underlies motility dysfunction in accordion zebrafish.
- Acetylcholine receptors enable the transport of rapsyn from the Golgi complex to the plasma membrane
- Synuclein accumulation is associated with cell‐specific neuronal death after spinal cord injury
- Acetylcholine receptor clustering is required for the accumulation and maintenance of scaffolding proteins.
- An acetylcholine receptor lacking both γ and ε subunits mediates transmission in zebrafish slow muscle synapses
- Function of neuromuscular synapses in the zebrafish choline-acetyltransferase mutant bajan.
- Zebrafish muscular disease models towards drug discovery
- A transmembrane protein required for acetylcholine receptor clustering in Caenorhabditis elegans
- Rhythmic motor activity evoked by NMDA in the spinal zebrafish larva.
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