Tau protein immunoreactivity in dementia of the Alzheimer type: II. Electron microscopy and pathogenetic implications. Effects of fixation on the morphology of the Alzheimer's abnormal filaments.
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Summary
Findings suggest that localization of excessive tau immunoreactivity with ribosomes might be the primary event and association of detectable tau immune activity with already assembled filaments might be an epiphenomenon; and the mode of fixation and subsequent preparatory procedures might alter the morphology of the Alzheimer's abnormal filaments.
- Type
- article
- Published
- 1989-03-01
- Cited by
- 30
- References
- 0
- OpenAlex
- https://openalex.org/W15181123
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:21209153
Keywords
Pathology, Senile plaques, Neurofibrillary tangle, Neurofilament, Electron microscope
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