Astrocyte apoptosis: implications for neuroprotection.
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Summary
It is found that incubation of cultured rat astrocytes in a Ca(2+)-containing medium after exposure to a Ca-2+-free medium causes an increase in intracellular Ca( 2+) concentration followed by apoptosis, and that NF-kappa B, reactive oxygen species, and enzymes such as calpain, xanthine oxidase, calcineurin and caspase-3 are involved in reperfusion-induced apoptosis.
- Type
- dissertation
- Published
- 2004-02-01
- Cited by
- 468
- References
- 327
- OpenAlex
- https://openalex.org/W15063528
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:40626951
Keywords
Molecular biology, Humanities, Gynecology, Biology, Medicine
References
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- Efeito da ingestão crônica de cafeína na atividade de enzimas antioxidantres, peroxidação de lipídeos e na produção de radicais livres em diferentes regiões do sistema nervoso central de ratos adultos
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- Histological study of the protective effect of melatonin on neural cells after neonatal hypoxia-ischemia.
- Alzheimer's factors in postischemic dementia.
- O amor nos tempos do crack : psicodinâmica, comportamento, biologia e uma proposição de estadiamento funcional
- Immunomodulatory function of astrocytes characterization and regulation of postanoid metabolism and cytokine synthesis
- A rat model of oligomeric forms of beta-amyloid (Aß) peptide: neuronal loss, synaptic alteration, astrogliosis, and calcium-binding proteins activation in vivo
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