Decreased transfusion requirements for patients receiving nonmyeloablative compared with conventional peripheral blood stem cell transplants from HLA-identical siblings.
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Summary
Red blood cell (RBC) and platelet transfusion requirements in patients given nonmyeloablative versus conventional peripheral blood stem cell (PBSC) transplants from HLA-matched siblings were compared and neither patient age, splenomegaly at transplantation, development of graft-versus-host disease, nor posttransplantation cytomegalovirus antigenemia or cytomeGalovirus disease had statistically significant influences on posttrans transplantation transfusions.
- Type
- article
- Published
- 2001-12-15
- Cited by
- 115
- References
- 24
- OpenAlex
- https://openalex.org/W11739160
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:3224450
Keywords
Computer vision, Artificial intelligence, Computer science, Machine vision, Position (finance)
References
- Nonmyeloablative stem cell transplantation and cell therapy as an alternative to conventional bone marrow transplantation with lethal cytoreduction for the treatment of malignant and nonmalignant hematologic diseases.
- Graft-v-host disease is associated with autoimmune-like thrombocytopenia.
- Delayed engraftment associated with splenomegaly in patients undergoing bone marrow transplantation for chronic myeloid leukaemia.
- Graft-versus-myeloma effect: proof of principle.
- Graft-versus-leukemia effect after allogeneic bone marrow transplantation for chronic lymphocytic leukemia.
- Engraftment of allogeneic hematopoietic progenitor cells with purine analog-containing chemotherapy: harnessing graft-versus-leukemia without myeloablative therapy.
- Stable mixed hematopoietic chimerism in DLA-identical littermate dogs given sublethal total body irradiation before and pharmacological immunosuppression after marrow transplantation.
- Neutropenia in allogeneic marrow transplant recipients receiving ganciclovir for prevention of cytomegalovirus disease: risk factors and outcome.
- Clinical bone marrow and blood stem cell transplantation
- Graft-versus-leukemia effect of donor lymphocyte transfusions in marrow grafted patients.
- Transplant-lite: induction of graft-versus-malignancy using fludarabine-based nonablative chemotherapy and allogeneic blood progenitor-cell transplantation as treatment for lymphoid malignancies.
- Autografting followed by nonmyeloablative immunosuppressive chemotherapy and allogeneic peripheral-blood hematopoietic stem-cell transplantation as treatment of resistant Hodgkin's disease and non-Hodgkin's lymphoma.
- Marrow toxicity of fractionated vs. single dose total body irradiation is identical in a canine model.
- Effect of splenectomy before bone-marrow transplantation on survival in chronic granulocytic leukaemia.
- Mixed chimerism: preclinical studies and clinical applications.
- Insensitivity of respiratory centre to carbon dioxide in the Enga people of New Guinea.
- Hematopoietic cell transplantation in older patients with hematologic malignancies: replacing high-dose cytotoxic therapy with graft-versus-tumor effects.
- Successful treatment of metastatic renal cell carcinoma with a nonmyeloablative allogeneic peripheral-blood progenitor-cell transplant: evidence for a graft-versus-tumor effect.
- Transplantation of bone marrow as compared with peripheral-blood cells from HLA-identical relatives in patients with hematologic cancers.
- Evidence for a graft-versus-tumor effect in a patient treated with marrow ablative chemotherapy and allogeneic bone marrow transplantation for breast cancer.
Cited by
- Intensive therapies in follicular non-Hodgkin lymphomas.
- Nonmyeloablative allogeneic stem-cell transplantation for hematologic malignancies: a systematic review.
- Blood and bone marrow transplantation for patients with Hodgkin's and non-Hodgkin's lymphoma.
- Trasplante no mieloablativo de células progenitoras hematopoyéticas. Mitos y realidades
- Mechanisms of the Antitumor Responses and Host-versus-Graft Reactions Induced by Recipient Leukocyte Infusions in Mixed Chimeras Prepared with Nonmyeloablative Conditioning: A Critical Role for Recipient CD4+ T Cells and Recipient Leukocyte Infusion-Derived IFN-γ-Producing CD8+ T Cells1
- An analysis of transfusion support in haematopoietic stem cell transplantation--report from a centre in India.
- The influence of blood group differences in allogeneic hematopoietic peripheral blood progenitor cell transplantation
- Antitumor effect of donor marrow graft rejection induced by recipient leukocyte infusions in mixed chimeras prepared with nonmyeloablative conditioning: critical role for recipient-derived IFN-gamma.
- Allogeneic hematopoietic cell transplantation for acute myeloid leukemia.
- Clinical Observation of Factors in the Efficacy of Blood Component Transfusion in Patients following Hematopoietic Stem Cell Transplantation
- Allogeneic hematopoietic cell transplantation as treatment for hematological malignancies: a review
- Effects on erythropoiesis of alemtuzumab‐containing reduced intensity and standard conditioning regimens
- Red blood cell-incompatible allogeneic hematopoietic progenitor cell transplantation
- Reduced-intensity allogeneic hematopoietic stem cell transplantation for acute leukemias: ‘what is the best recipe?’
- Clinical relevance of recipient leukocyte infusion as antitumor therapy following nonmyeloablative allogeneic hematopoietic cell transplantation.
- Non-myeloablative hematopoietic cell transplant for treatment of nonmalignant disorders in children
- Transfusions after nonmyeloablative or reduced-intensity conditioning regimens
- A pilot study of reduced intensity conditioning and allogeneic stem cell transplantation from unrelated cord blood and matched family donors in children and adolescent recipients
- Review of “Minitransplantation”: Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation
- Lower costs associated with hematopoietic cell transplantation using reduced intensity vs high-dose regimens for hematological malignancy
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