Rationale and design of a secondary prevention trial of antibiotic use in patients after myocardial infarction: the WIZARD (weekly intervention with zithromax [azithromycin] for atherosclerosis and its related disorders) trial.
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Summary
The WIZARD trial is a secondary prevention study that is assessing the impact of a 3-month course of azithromycin compared with placebo on the progression of clinical coronary heart disease.
- Type
- article
- Published
- 2000-06-01
- Cited by
- 74
- References
- 39
- OpenAlex
- https://openalex.org/W10839762
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:35308384
Keywords
Geography
References
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- Rabbit model for Chlamydia pneumoniae infection
- Persistent chlamydiae: from cell culture to a paradigm for chlamydial pathogenesis.
- Discrete sequential boundaries for clinical trials
- Azithromycin-induced block of elementary body formation in Chlamydia trachomatis
- The in-vitro antibiotic susceptibility of Chlamydia pneumoniae.
- Rationale for the Use of Azithromycin as Mycobacterium avium Chemoprophylaxis
- Poor correlation between microimmunofluorescence serology and polymerase chain reaction for detection of vascular Chlamydia pneumoniae infection in coronary artery disease patients
- Inhalation of levomepromazine in severe acute asthma.
- Low Density Lipoprotein Oxidation and Its Pathobiological Significance*
- High prevalence of Chlamydia pneumoniae DNA in peripheral blood mononuclear cells in patients with cardiovascular disease and in middle-aged blood donors.
- Plasma hydrogen peroxide production in hypertensives and normotensive subjects at genetic risk of hypertension
- Serological evidence of an association of a novel Chlamydia, TWAR, with chronic coronary heart disease and acute myocardial infarction.
- Once weekly azithromycin therapy for prevention of Mycobacterium avium complex infection in patients with AIDS: a randomized, double-blind, placebo-controlled multicenter trial.
- Infections caused by Chlamydia pneumoniae strain TWAR.
- In vitro activities of azithromycin, clarithromycin, L-ofloxacin, and other antibiotics against Chlamydia pneumoniae
- Treatment of Chlamydia pneumoniae infection in adult asthma: a before-after trial.
- Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)
- Seroepidemiology of Chlamydia pneumoniae TWAR infection in Seattle families, 1966-1979.
Cited by
- Cardiac protection by pharmacological modulation of inflammation
- Antibody levels against Chlamydia pneumoniae and outcome of roxithromycin therapy in patients with acute myocardial infarction
- Chlamydia pneumoniae: detection and geotyping of infections in atherosclerotic carotid arteries
- Avaliação dos efeitos antitrombótico e antiinflamatório da roxitromicina : experimento randomizado em coelhos
- Infection and Inflammation in progression of Atherosclerosis : the role of Chlamydiae pneumoniae infection in different mouse models
- Die Wirkung von Roxithromycin auf die Prognose von Patienten mit Koronardilatation bei koronarer Herzerkrankung
- Adverse events in people taking macrolide antibiotics versus placebo for any indication.
- Novel PCR-EIA method for the detection of Chlamydia pneumoniae in respiratory specimens.
- Emerging concepts in disease management: a role for antimicrobial therapy in coronary artery disease
- Antibiotics for vascular diseases: a meta-analysis of randomized controlled trials.
- Chlamydia pneumoniae and Atherosclerosis: No Way-Out or Long Way?
- Recurrent pneumonia due to persistent Chlamydia pneumoniae infection.
- Metabolic syndrome, C-reactive protein, and prognosis in patients with established coronary artery disease.
- Anti-inflammatory effects of macrolide antibiotics.
- Antibiotic use and risk of ischemic stroke in the elderly.
- Inflammation and coronary artery disease.
- Chlamydia pneumoniae and atherosclerosis
- Use of antibiotics is not associated with decreased risk of myocardial infarction among patients with diabetes.
- Azithromycin inhibits interleukin-6 but not fibrinogen production in hepatocytes infected with cytomegalovirus and chlamydia pneumoniae.
- Multiple Infections and Subsequent Cardiovascular Events in the Heart Outcomes Prevention Evaluation (HOPE) Study
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