Measuring VEGF-Flk-1 activity and consequences of VEGF-Flk-1 targeting in vivo using intravital microscopy: clinical applications.

Keywords

Parallels, Happening, Natural resource, Resource (disambiguation), Relation (database)

References

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• Characterization of Angiogenesis and Microcirculation of High–Grade Glioma: An Intravital Multifluorescence Microscopic Approach in the Athymic Nude MousePeter Vajkoczy, Lothar Schilling, Axel Ullrich — 1998
• Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF.Jocelyn Holash, Peter C. Maisonpierre, Debra Compton — 1999
• Inhibition of tumor growth, angiogenesis, and microcirculation by the novel Flk-1 inhibitor SU5416 as assessed by intravital multi-fluorescence videomicroscopy.Peter Vajkoczy, Michael D. Menger, Brigitte Vollmar — 1999
• Tumor induction of VEGF promoter activity in stromal cells.Dai Fukumura, Ramnik J. Xavier, Takeyuki Sugiura — 1998
• Dominant-negative inhibition of Flk-1 suppresses the growth of many tumor types in vivo.B Millauer, M P Longhi, Karl H. Plate — 1996
• SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types.T. Annie T. Fong, Laura K. Shawver, Li Sun — 1999
• Angiogenic factors.Judah Folkman, Michael Klagsbrun — 1987
• What is the evidence that tumors are angiogenesis dependent?J. Folkman — 1990

Cited by

• Intravital microscopy in the mouse dorsal chamber model for the study of solid tumors.Véronique Baron, John Welsh, Parisa Abedinpour — 2011
• Expansion of endothelial surface by an increase of vessel diameter during tumor angiogenesis in experimental and hepatocellular and pancreatic cancer.Eduard Ryschich — 2004
• Influence of soluble or matrix‐bound isoforms of vascular endothelial growth factor‐A on tumor response to vascular‐targeted strategiesSimon Akerman, Matthew Fisher, Rachel Daniel — 2013
• The immunopharmacologic potential of Semaxanib and new generation directed therapeutic drugs: Receptor tyrosine kinase regulation with anti-tumorigenensis/angiogenesis properties.John J. Haddad — 2012
• Hydrodynamics-based gene delivery of naked DNA encoding fetal liver kinase-1 gene effectively suppresses the growth of pre-existing tumorsHiroyuki Yazawa, Takaya Murakami, HM Li — 2006
• The vascular-targeting fusion toxin VEGF121/rGel inhibits the growth of orthotopic human bladder carcinoma tumors.Khalid A. Mohamedali, Daniel Kedar, Paul Sweeney — 2005
• Targeted therapy using novel agents in the treatment of non-small-cell lung cancer.Roy S. Herbst — 2002
• Quantitative Angiogenesis Assays in vivo – A ReviewJurjees Hasan, Steven D. Shnyder, M. Bibby — 2004
• Intravital microscopy of tumor angiogenesis and regression in the dorsal skin fold chamber: mechanistic insights and preclinical testing of therapeutic strategiesGudrun E. Koehl, Andreas Gäumann, Edward K. Geissler — 2009
• Angiogenesis inhibitors in lung cancerEdward S. Kim, Roy S. Herbst — 2002
• Factor de crecimiento de endotelio vascular y su relación clínica en carcinomas papilares de tiroides con invasión extracapsular Expression of vascular endothelial growth factor and KDR in papillary thyroid carcinoma with extracapsular invasionRogelio González‐González, Ronell Bologna Molina, Nelly Molina‐Frechero — 2009
• Novel tempeh (fermented soyabean) isoflavones inhibit in vivo angiogenesis in the chicken chorioallantoic membrane assaySerafim Kiriakidis, Oliver Högemeier, Susanne Starcke — 2005
• Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors.Gabriele Bergers, Steven Song, Nicole Meyer-Morse — 2003
• Malignant glioma drug discovery – targeting protein kinasesSith Sathornsumetee, Kaitlyn A Vredenburgh, Kathryn P. Lattimore — 2007
• Celecoxib Inhibits Vascular Endothelial Growth Factor Expression in and Reduces Angiogenesis and Metastasis of Human Pancreatic Cancer via Suppression of Sp1 Transcription Factor ActivityDaoyan Wei, Liwei Wang, Yanjuan He — 2004
• Detection of early antiangiogenic effects in human colon adenocarcinoma xenografts: in vivo changes of tumor blood volume in response to experimental VEGFR tyrosine kinase inhibitor.Young Ro Kim, Anna Yudina, Jose-Luis Figueiredo — 2005
• A Phase I study of the angiogenesis inhibitor SU5416 (semaxanib) in solid tumours, incorporating dynamic contrast MR pharmacodynamic end pointsAnne O’Donnell, Anwar R. Padhani, Carmel Hayes — 2005
• Quantitation of angiogenesis and antiangiogenesis in vivo, ex vivo and in vitro - an overview.Mahtab Bahramsoltani — 2009
• Transcriptional activity and alternative splice mRNA forms of Flt-1, Flk-1 genes in the estimation of risk progression of squamous intraepithelial lesions and cervical cancerBogdan Michalski, Dariusz Kuśmierz, Ryszard Poręba — 2003
• Vascular Endothelial Growth Factor in Malignant Disease of the Central Nervous SystemD. Stefanik — 2013

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