TNF receptor 1 (TNFR1) and CD95 are not required for T cell deletion after virus infection but contribute to peptide‐induced deletion under limited conditions
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Summary
It is shown that TNFR1 and CD95 do not contribute to the decline of antigen‐specific cytotoxic T lymphocytes after virus infection, and under certain conditions, both TNfr1 andCD95 appear to cooperate in CD8+ T cell deletion.
- Type
- article
- Published
- 2000-02-01
- Cited by
- 88
- References
- 22
- Access
- Open access
- OpenAlex
- https://openalex.org/W10671227
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:39755618
Keywords
Computer science
References
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- T cell receptor-dependent cell death of T cell hybridomas mediated by the CD30 cytoplasmic domain in association with tumor necrosis factor receptor-associated factors
- A potential mechanism of "cross-talk" between the p55 tumor necrosis factor receptor and Fas/APO1: proteins binding to the death domains of the two receptors also bind to each other
- Supraoptimal Peptide–Major Histocompatibility Complex Causes a Decrease in Bcl-2 Levels and Allows Tumor Necrosis Factor α Receptor II–mediated Apoptosis of Cytotoxic T Lymphocytes
Cited by
- CD28-dependent Activation of Protein Kinase B/Akt Blocks Fas-mediated Apoptosis by Preventing Death-inducing Signaling Complex Assembly
- Factors contributing to autoimmune disease.
- Caspase 3 is not essential for the induction of anergy or multiple pathways of CD8+ T‐cell death
- Contribution of LCMV transgenic models to understanding T lymphocyte development, activation, tolerance, and autoimmunity.
- Tissue-dependent T Cell Apoptosis and Transcriptional Regulation of Memory CD8+T Cell Differentiation During Viral Infections: A Dissertation
- Decisions on the road to memory.
- Peripheral tolerance and organ specific autoimmunity.
- Autophagy and lymphocyte homeostasis.
- The role of inflammation in the generation and maintenance of memory T cells.
- Regulation of Early T Cell Activation by TNF Superfamily Members TNF and FASL: A Dissertation
- T-cell signalling and autoimmunity: molecular mechanisms of disease
- Defining a T cell-intrinsic role for MYD88 during LCMV infection
- Regulation of CD4+ T-cell contraction during pathogen challenge
- Different Programs of Activation-Induced Cell Death Are Triggered in Mature Activated CTL by Immunogenic and Partially Agonistic Peptide Ligands1
- Distinct Requirements for Deletion versus Anergy during CD8 T Cell Peripheral Tolerance In Vivo1
- IL-15 Regulates CD8+ T Cell Contraction during Primary Infection1
- The Contraction Phase of Virus-Specific CD8+ T Cells Is Unaffected by a Pan-Caspase Inhibitor1
- T cells as sources and targets of TNF: implications for immunity and autoimmunity.
- Modeling T‐ and B‐cell growth and differentiation
- Tyk2 Signaling in Host Environment Plays an Important Role in Contraction of Antigen-Specific CD8+ T Cells following a Microbial Infection1
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