Tumor necrosis factor-alpha induces adhesion molecule expression through the sphingosine kinase pathway.
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Summary
It is demonstrated that the SKase pathway through the generation of S1P is critically involved in mediating TNFalpha-induced endothelial cell activation.
- Type
- article
- Published
- 1998-11-24
- Cited by
- 448
- References
- 33
- Access
- Open access
- OpenAlex
- https://openalex.org/W9826677
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:39207930
Keywords
Humanities, Philosophy
References
- Tumor Necrosis Factor α-Induced E-selectin Expression Is Activated by the Nuclear Factor-κB and c-JUN N-terminal Kinase/p38 Mitogen-activated Protein Kinase Pathways*
- Sphingosine 1-phosphate signalling through the G-protein-coupled receptor Edg-1.
- Leukocyte-endothelial adhesion molecules.
- Identification of a putative membrane receptor for the bioactive phospholipid, lysophosphatidic acid.
- Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1.
- MAP kinases in mitogenesis and development.
- p38 and Extracellular Signal-regulated Kinase Mitogen-activated Protein Kinase Pathways Are Required for Nuclear Factor-κB p65 Transactivation Mediated by Tumor Necrosis Factor*
- Transforming growth factor-beta inhibits E-selectin expression on human endothelial cells.
- Sphingolipid metabolism and cell growth regulation
- Adhesion receptors of the immune system
- Fas-induced apoptosis of T cells occurs independently of ceramide generation.
- Functional roles of sphingosine, sphingosine 1-phosphate, and methylsphingosines: in regard to membrane sphingolipid signaling pathways.
- Signal Transduction by DR3, a Death Domain-Containing Receptor Related to TNFR-1 and CD95
- Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens
- Sphingosine-1-phosphate, a novel lipid, involved in cellular proliferation
- Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate
- Intracellular calcium release mediated by sphingosine derivatives generated in cells.
- The sphingomyelin signal transduction pathway mediates apoptosis for tumor necrosis factor, Fas, and ionizing radiation.
- Molecular Cloning and Functional Characterization of Murine Sphingosine Kinase*
- Tumor necrosis factor (TNF).
Cited by
- Phospholipid composition of reconstituted high density lipoproteins influences their ability to inhibit endothelial cell adhesion molecule expression.
- Bioactive sphingolipids in the modulation of the inflammatory response.
- Tumor necrosis factor‐α exerts pro‐myogenic action in C2C12 myoblasts via sphingosine kinase/S1P2 signaling
- The outs and the ins of sphingosine-1-phosphate in immunity
- Sphingosine 1-Phosphate Mediates Hyperalgesia via a Neutrophil-Dependent Mechanism
- Sphingosine-1-Phosphate (S1P) and S1P Signaling Pathway: Therapeutic Targets in Autoimmunity and Inflammation
- Effect of long-distance transportation on serum metabolic profiles of steer calves.
- Regulation of the sphingosine kinase/sphingosine 1-phosphate pathway.
- Cellular and molecular mechanisms of venous leg ulcers development--the "puzzle" theory.
- Avaliação da participação de receptores do tipo toll na indução de resposta imune por Lactobacillus delbrueckii UFV H2b20 .
- Lysophospholipid activation of G protein-coupled receptors.
- Lysophospholipid Receptors in the Nervous System
- Therapeutic potential of targeting SK1 in human cancers.
- Optimising stem cell therapy for liver disease through modulation of sphingosine 1-phosphate signalling
- Cardiovascular effects of sphingosine-1-phosphate (S1P).
- Cannabinoids as neuroprotective agents : a mechanistic study
- Sphingolipid metabolizing enzymes as novel therapeutic targets.
- Adipose tissue and ceramide biosynthesis in the pathogenesis of obesity.
- INTRACELLULAR TARGETS OF SPHINGOSINE-1-PHOSPHATE
- Expression levels of bioactive sphingolipid genes in newly diagnosed and drug-resistant chronic myeloid leukemia patients and their impact on the clinical progress
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