Genetic control of serum IgE levels and asthma: linkage and linkage disequilibrium studies in an isolated population.
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Summary
It is concluded that allelic variation at chromosome 5q31 is not likely to contribute to inheritance of serum IgE levels or the development of asthma in this Finnish subpopulation.
- Type
- article
- Published
- 1997-11-01
- Cited by
- 101
- References
- 35
- OpenAlex
- https://openalex.org/W9328470
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:17109435
Keywords
Computer science, Semantic similarity, Overlay, Semantic Web Stack, Semantic computing
References
- Genetic susceptibility to asthma--bronchial hyperresponsiveness coinherited with a major gene for atopy.
- Evidence for a locus regulating total serum IgE levels mapping to chromosome 5.
- Atopic disease and immunoglobulin E in twins reared apart and together.
- The 1993–94 Généthon human genetic linkage map
- Fine mapping of the congenital chloride diarrhea gene by linkage disequilibrium.
- The apolipoprotein E/CI/CII gene cluster and late-onset Alzheimer disease.
- A rapid dosimetric method with controlled tidal breathing for histamine challenge. Repeatability and distribution of bronchial reactivity in a clinical material.
- A comprehensive genetic map of the human genome based on 5,264 microsatellites
- Allelic association but only weak evidence for linkage to the apolipoprotein E locus in late-onset Swedish Alzheimer families.
- A genome-wide search for quantitative trait loci underlying asthma
- Generation and analysis of interleukin-4 deficient mice.
- Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease.
- Methacholine bronchial challenge using a dosimeter with controlled tidal breathing.
- Serum IgE levels in twins.
- A comprehensive human linkage map with centimorgan density. Cooperative Human Linkage Center (CHLC).
- The gene for a recessively inherited human childhood progressive epilepsy with mental retardation maps to the distal short arm of chromosome 8.
- Spirometric studies in non-smoking, healthy adults.
- Mutations of the Down–regulated in adenoma (DRA) gene cause congenital chloride diarrhoea
- Linkage analysis of IL4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations.
- Disease gene mapping in isolated human populations: the example of Finland.
Cited by
- Ethnic differences in genetic susceptibility to atopy and asthma.
- Polymorphism of the Interleukin- and Interleukin Receptor Genes: Population Distribution and Association with Atopic Asthma
- Molecular Genetics of Non-Syndromic Cleft Palate and Van Der Woude Syndrome
- Positional cloning and pathway analysis of the asthma susceptibility gene, NPSR1
- The -590C/TIL4 single-nucleotide polymorphism as a genetic factor of atopic allergy.
- Juxtaposed regions of extensive and minimal linkage disequilibrium in human Xq25 and Xq28
- Immunopathogenesis of Asthma and Atopic Diseases – The specific Role of a selected Panel of Genes in human T helper Cell Differentiation
- FAMILIAL AGGREGATION AND RISK FACTORS FOR ASTHMA AND HAY FEVER AMONG FINNISH ADOLESCENT TWINS — A TWIN FAMILY STUDY
- Gene mapping by linkage and association analysis
- A cluster of seven tightly linked polymorphisms in the IL-13 gene is associated with total serum IgE levels in three populations of white children.
- The IL9R region contribution in asthma is supported by genetic association in an isolated population
- An IL13 coding region variant is associated with a high total serum IgE level and atopic dermatitis in the German multicenter atopy study (MAS-90).
- Linkage analysis of the 5q31–33 candidate region for asthma in 240 UK families
- Efficient association mapping of quantitative trait loci with selective genotyping.
- Efficient multipoint linkage analysis through reduction of inheritance space.
- Major histocompatibility complex (MHC)-linked microsatellite markers in a founder population.
- Disequilibrium mapping of a quantitative-trait locus in an expanding population.
- Mutation screening of interferon regulatory factor 1 gene (IRF‐1) as a candidate gene for atopy/asthma
- Immunological parameters and gene polymorphisms (C-590T IL4, C-597A IL10) in severe bronchial asthma in children from the Krasnoyarsk region, West Siberia
- Chromosome 5q candidate genes in coeliac disease: genetic variation at IL4, IL5, IL9, IL13, IL17B and NR3C1.
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