Paraoxonase is reduced in patients with growth hormone deficiency: A novel risk factor for atherosclerosis
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Summary
The data support that GHD is characterized by an imbalance between oxidant and antioxidant factors, which may contribute to the increased atherogenic risk in patients with GHD.
- Type
- article
- Published
- 2013-04-01
- Cited by
- 6
- References
- 36
- Access
- Open access
- OpenAlex
- https://openalex.org/W5655976
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:35128234
Keywords
PON1, Malondialdehyde, Medicine, Internal medicine, Paraoxonase
References
- Immunohistochemical analysis of paraoxonases‐1 and 3 in human atheromatous plaques
- Antioxidant protection against hypochlorous acid in human plasma.
- The human serum paraoxonase polymorphism: identification of phenotypes by their response to salts.
- Lipid peroxidation and its role in atherosclerosis.
- Oxidative stress and antioxidant defenses in serum of patients with non-alcoholic steatohepatitis.
- Evidence for membrane lipid peroxidation during the in vivo aging of human erythrocytes.
- Genetic and environmental factors modulating serum concentrations and activities of the antioxidant enzyme paraoxonase-1.
- Proinflammatory Cytokines But Not Acute Phase Serum Amyloid A Or C-Reactive Protein, Downregulate Paraoxonase 1 (Pon1) Expression By Hepg2 Cells
- Serum paraoxonase 1 activity and malondialdehyde levels in patients with ulcerative colitis
- Paraoxonase (PON1) deficiency is associated with increased macrophage oxidative stress: studies in PON1-knockout mice.
- Determination of oxidative protein and lipid damage in adult hypopituitary patients with GH deficiency
- Detection and localization of tumor necrosis factor in human atheroma.
- Investigation of protein oxidation and lipid peroxidation in patients with rheumatoid arthritis
- Increase of adhesion molecules, fibrinogen, type‐1 plasminogen activator inhibitor and orosomucoid in growth hormone (GH) deficient adults and their modulation by recombinant human GH replacement
- Reactive oxygen species in living systems: source, biochemistry, and role in human disease.
- Paraoxonase inhibits high-density lipoprotein oxidation and preserves its functions. A possible peroxidative role for paraoxonase.
- Beginning to end: cardiovascular implications of growth hormone (GH) deficiency and GH therapy.
- Paraoxonase 1 and atherosclerosis: is the gene or the protein more important?
- Impact of growth hormone (GH) treatment on cardiovascular risk factors in GH-deficient adults: a Metaanalysis of Blinded, Randomized, Placebo-Controlled Trials.
- Role of glutathione in immunity and inflammation in the lung
Cited by
- Reconstituted High-Density Lipoprotein Containing Human Growth Hormone-1 Shows Potent Tissue Regeneration Activity with Enhancement of Anti-Oxidant and Anti-Atherosclerotic Activities
- The genetic association between PON1 polymorphisms and osteonecrosis of femoral head
- Effect of radiotherapy on activity and concentration of serum paraoxonase-1 in breast cancer patients
- Serum paraoxonase activity and total sialic acid in sheep with foot and mouth disease
- Oxidative Stress is Involved in the Occurrence and Development of Lower Extremity Atherosclerotic Disease
- Improvement of HDL
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