Inhibition of peroxisomal beta‐oxidation and brain development in rats
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Summary
Under the experimental conditions, thioridazine causes accumulation of C24 and C26 fatty acids in pup brain lipids, an effect the authors consider to be a typical consequence of inhibited peroxisomal beta‐oxidation.
- Type
- article
- Published
- 1989-01-01
- Cited by
- 8
- References
- 37
- OpenAlex
- https://openalex.org/W2527823
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:30192127
Keywords
Political science
References
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- Microperoxisomes in the central nervous system of the postnatal rat.
- Quantitative and compositional changes in myelin of undernourished and protein malnourished rat brains.
- Effects of undernutrition on myelination in rat corpus callosum
- Effects of undernutrition on cell formation in the rat brain and specially on cellular composition of the cerebellum.
- Preliminary note on the size and condition of the central nervous system in albino rats experimentally stunted
- Importance of exogenous saturated fatty acids during brain development and myelination in mice
- A stereological analysis of the cerebellar granule and purkinje cells of 30‐day‐old and adult rats undernourished during early postnatal life
- Influence of hormones and undernutrition on brain development in newborn rats.
- GLIAL VERSUS NEURONAL ORIGIN OF MYELIN PROTEINS AND GLYCOPROTEINS STUDIED BY COMBINED INTRAOCULAR AND INTRACRANIAL LABELLING
- The relationship between nutritional adequacy and brain myelin accumulation: a comparison of varying degrees of well fed and undernourished rats.
- Letter: Species differences in experimental teratogenesis by tranquillising agents.
- Myelin synthesis during postnatal nutritional deprivation and subsequent rehabilitation.
- Pseudo-Zellweger syndrome: deficiencies in several peroxisomal oxidative activities.
Cited by
- On the role of the peroxisome in cell differentiation and carcinogenesis
- Immunocytochemical localization of acyl-CoA oxidase in the rat central nervous system
- Experimental inhibition of peroxisomal β‐oxidation in rats: Influence on brain myelination
- Lipopolysaccharide-induced peroxisomal dysfunction exacerbates cerebral white matter injury: attenuation by N-acetyl cysteine.
- Modulation of peroxisome proliferator‐activated receptor‐α activity by N‐acetyl cysteine attenuates inhibition of oligodendrocyte development in lipopolysaccharide stimulated mixed glial cultures
- Altered adrenocortical response under the influence of experimentally increased serum very long chain fatty acids in rats.
- On the role of the peroxisome in ontogeny, ageing and degenerative disease.
- Thioridazine induces lipid peroxidation in myelin of rat brain.
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