Conformation in solution of porcine brain natriuretic peptide determined by combined use of nuclear magnetic resonance and distance geometry.

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Summary

The conformation in solution of porcine brain natriuretic peptide was determined by combined use of NMR spectroscopy and distance geometry using a set of 157 inter-proton-distance constraints derived from the two-dimensional NOE spectra and three hydrogen bond constraints obtained from analysis of the temperature dependence of labile protons.

Type
article
Published
1990-10-01
Cited by
11
References
35
Access
Open access

Keywords

Computer science

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