The antimalarial effect of iron chelators: studies in animal models and in humans with mild falciparum malaria.
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Summary
Results of the double-blind, placebo controlled trial of DF in humans with asymptomatic parasitemia provided unequivocal evidence that this iron-chelating agent has antimalarial activity, and data indicate that other orally effective iron chelators may have superior antimalaria activity in vivo.
- Type
- article
- Published
- 1992-08-15
- Cited by
- 50
- References
- 23
- OpenAlex
- https://openalex.org/W1431886
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:44431474
Keywords
Blended learning, Computer science, Mathematics education, Psychology, Educational technology
References
- Production of leukemic blast growth factor by a human bladder carcinoma cell line.
- 1,2-Dimethyl-3-hydroxypyrid-4-one, an orally active chelator for treatment of iron overload.
- Stage-dependent effect of deferoxamine on growth of Plasmodium falciparum in vitro.
- Iron metabolism in murine erythroleukaemic cells
- Coordination of calcium by iron enterobactin
- Plasmodium falciparum: inhibition in vitro with lactoferrin, desferriferrithiocin, and desferricrocin.
- OPERATIVE STRATEGY FOR PHAEOCHROMOCYTOMAS LOCALISED BY [131I]-m-IODOBENZYLGUANIDINE SCINTIGRAPHY
- Plasmodium falciparum takes up iron from transferrin
- Desferrioxamine Suppresses Plasmodium falciparum in Aotus Monkeys 1
- Effect of Iron Deficiency and Desferrioxamine on DNA Synthesis in Human Cells
- Selection of hydroxypyridin-4-ones for the treatment of iron overload using in vitro and in vivo models.
- Deferoxamine inhibition of malaria is independent of host iron status
- Plasmodium falciparum in culture: use of outdated erthrocytes and description of the candle jar method.
- A reappraisal of the effects of iron and desferrioxamine on the growth of Plasmodium falciparum‘in vitro’: the unimportance of serum iron
- Altered membrane transport of malaria-infected erythrocytes: a possible pharmacologic target.
- Plasmodium falciparum: inhibition of in vitro growth by desferrioxamine.
- Concentration from continuous culture of erythrocytes infected with trophozoites and schizonts of Plasmodium falciparum.
- Iron mobilization from hepatocyte monolayer cultures by chelators: the importance of membrane permeability and the iron-binding constant.
- MALARIA AND IRON
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- In vitro and in vivo antitumour studies of a new thiosemicarbazide derivative and its complexes with 3d-metal ions
- Biological Models in Radiopharmaceutical Development
- Diet and Human Immune Function
- Iron chelating agents for treating malaria.
- Antimalarial effect of iron chelators.
- Investigação do caráter evolutivo/adaptativo do comportamento-doente na transmissão de agentes infecciosos
- Probing the Chloroquine Resistance Locus of Plasmodium falciparum with a Novel Class of Multidentate Metal(III) Coordination Complexes*
- The Treatment of Malaria with Iron Chelators
- Design of iron chelators with therapeutic application
- Overview Anti-infectives: The treatment of malaria with iron chelators
- Stepwise MLR and PCR QSAR study of the pharmaceutical activities of antimalarial 3-hydroxypyridinone agents using B3LYP/6-311++G** descriptors
- Design of clinically useful iron(III)‐selective chelators
- The discovery, synthesis and antimalarial evaluation of natural product-based polyamine alkaloids
- Antimalarial Iron Chelator FBS0701 Blocks Transmission by Plasmodium falciparum Gametocyte Activation Inhibition
- Betainohydroxamic acid chloride.
- Conjugation to 4-aminoquinoline improves the anti-trypanosomal activity of Deferiprone-type iron chelators.
- Short day lengths attenuate the symptoms of infection in Siberian hamsters
- Nickel(II) thiohydrazide and thiodiamine complexes: synthesis, characterization, antibacterial, antifungal and thermal studies.
- Iron chelators as therapeutic agents against Pneumocystis carinii
- Basic 3-hydroxypyridin-4-ones: potential antimalarial agents.
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